NMJ DRUGS

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7 Terms

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α-bungarotoxin

Irreversible competitive antagonist of Nm nAChR and α7 nAChRs

2
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Suxamethonium/succinylcholine

Long lasting Nm agonist → depolarising block

3
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D-tubocurarine

Competitive nAChRs antagonist → non-depolarising block

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Rocuronium

Synthetic competitive antagonist of nAChR → non-depolarising block

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Atracurium

Synthetic competitive antagonist of nAChR → non-depolarising block

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Aminoglycoside

Inhibit CaV channels → inhibit ACh release

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Tetracycline

Chelates (i.e. buffers) Ca2+ to inhibit ACh release