NMJ DRUGS
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Last updated 12:19 PM on 11/11/25
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7 Terms
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α-bungarotoxin
Irreversible competitive antagonist of Nm nAChR and α7 nAChRs
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Suxamethonium/succinylcholine
Long lasting Nm agonist → depolarising block
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D-tubocurarine
Competitive nAChRs antagonist → non-depolarising block
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Rocuronium
Synthetic competitive antagonist of nAChR → non-depolarising block
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Atracurium
Synthetic competitive antagonist of nAChR → non-depolarising block
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Aminoglycoside
Inhibit CaV channels → inhibit ACh release
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Tetracycline
Primary clinical use: antibiotic
Side effect: Chelates (i.e. buffers) Ca2+ to inhibit ACh release
So: overuse or high doses of tetracyclines can cause muscle weakness
Note 
Flashcards (23)