Psychopharmacology Exam #3

marijuana

spanish translation of cannabis

the year was marijuana listed as a schedule 1 drug

1970

the decade recreational drug use was made legal

2010s

the decade marijuana was criminalized 

1970s

3 main strains of cannabis

Indica, sativa, ruderalis

two main chemicals in cannabis

THC and CBD

entourage effect 

responsible for the unique high created from different strands 

sativa

higher THC, lower CBD; daytime use, supports immune system, relieves pain

indica

higher CBD, lower THC; nighttime use, sedation, reduces anxiety

forms of cannabis

dried, dabbing, edibles

Absorption of marijuana

smoking is similar to an IV due to its profile in plasma

vaporizers

vaporizes cannabis plants using hot air; less harmful than traditional smoking 

edibles

cannabis → butter → food; better for therapeutic use

half life of THC for naive users

1 hour

THC metabolite half-lives

up to 3 days

excretion of sativa

bile and feces

physiological effects of cannabis

increased heart rate, red eyes, bronchial dilation 

possible behavior outcomes of cannabis

relaxation, disinhibition, impaired motor skills, memory deficits

legal driving limit of cannabis

5ng/ml

Cannabis concentrates in 

frontal and occipital cerebral cortex, limbic structures, basal ganglia, dopamine regions