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Domain
The highest level in biological classification:
Bacteria
Archaea
Eukarya
Eukaryote
Organism composed of one or more eukaryotic cells; members of the domain Eukarya.
Eukaryotic Cell
Cell type characterized by a membrane-bound nucleus.
Prion
An acellular infectious agent consisting only of protein.
Prokaryote
Single-celled organism consisting of a prokaryote cell; members of the domains Bacteria and Archaea.
Prokaryotic Cell
Cell type characterized by the lack of membrane-bound nucleus.
Viroid
An acellular infectious agent consisting only of RNA.
Microbe
General term encompassing microorganisms and acellular infectious agents such as viruses.
Spontaneous Generation
Discredited belief that organisms can arise from non-living matter.
Biogenesis
The production of living things from other living things, as opposed to spontaneous generation.
Ferdinand Cohn
Discovered endospores.
Endospores
An extraordinarily resistant dormant cell produced by some types of bacteria (heat-resistant).
Germ Theory of Disease
Idea that infectious diseases are caused by microorganisms.
Normal microbiota
The group of microorganisms that colonize the body surfaces but do not usually cause disease.
Microbiome
The community of microorganisms, as well as their genetic information, in a given environment.
Commercial benefits of microorganisms
Microbes make life more comfortable for humans:
Food production (Bread, beer, wine, cheese, yogurt, buttermilk, sauerkraut, pickles, etc.)
Biodegradation of environmental pollutants (clean water and soil)
Produce valuable products (hydrogen, ethanol, oils, antibiotics, etc.)
Biotechnology (genetic engineering)
Pathogen
Disease-causing microbe.
Emerging infectious diseases (EIDs)
New diseases and diseases increasing in incidence or geographic range.
Genus
Taxonomic category of related organisms, usually containing several species. The first name of an organism in the Binomial System of Nomenclature (capitalized).
Species
A group of closely related strains; the basic unit of taxonomy (not capitalized).
Strain
A pure culture isolate; genetic variant within a species.
Bacteria
Single-celled prokaryotes:
rigid cell walls that contain peptidoglycan
move using flagella
Coccus
A spherical cell that may be flattened on one end or slightly oval.
Rod or bacillus
A cylindrical cell. One short enough to be confused with a coccus is called a coccobacillus.
Vibrio
A short, curved rod.
Spirillum
A curved rod long enough to form spirals.
Spirochete
A long, spiral-shaped cell with a flexible cell wall and a unique mechanism of motility.
Plemorphic
Not an actual shape, but refers to bacteria that characteristically vary in their shape.
Diplococcus
A pair of cocci.
Eukarya
Include fungi, algae, protozoa, and helminths (worms).
Protist
A eukaryotic organism other than a plant, animal, or fungus; may be unicellular or multicellular.
Fungi
Heterotrophic eukaryotic organisms containing chitin in the cell wall.
Mycelium
A densely branched network of the hyphae of a fungus.
Algae
Eukaryotic photosynthetic organisms with relatively simple reproductive structures and no organized vascular spasms.
Protozoa
Heterotrophic unicellular eukaryotic organisms that are not fungi:
do not have a rigid cell wall
Helminths
Worms; often have complex life cycles.
Virus
An acellular infectious agent consisting of nucleic acid surrounded by a protein coat.
Viroid
An infectious agent of plants that consists only of RNA.
Atom
The basic unit of matter.
Buffer
A chemical that stabilizes the pH of a solution.
Covalent Bond
A chemical bond formed when two atoms share electrons.
Hydrogen Bond
The attraction between a hydrogen atom in a polar molecule and an electronegative atom in the same or another polar molecule.
Ion
An atom or molecule that has gained or lost one or more electrons.
Ionic Bond
A chemical bond resulting from the attraction between positively and negatively charged ions.
Molecule
Two or more atoms held together by covalent bonds.
Nucleic Acid
A macromolecule consisting of one or two nucleotide chains; DNA or RNA.
Organic Compound
A compound that has a carbon atom covalently bonded to a hydrogen atom.
pH
A measure of the hydrogen ion concentration or acidity of a solution on a scale of 0-14.
Protein
A macromolecule consisting of one or more chains of amino acids.
Carbon, Hydrogen, Oxygen, Nitrogen, Phosphorus, Sulfur
The 6 most common elements in biology.
Lewis Symbol
Uses the element symbol and indicates the number of valence electrons using dots.
Electrolytes
Salts that conduct electricity when dissolved in water.
Non-polar covalent bond
Bond formed by sharing electrons between atoms that have equal attraction for the electrons.
Polar covalent bond
Bond formed by sharing electrons between atoms that have unequal attraction for the electrons.
Mole
Amount of a chemical in grams that contains 6.022 x 10^23 particles.
Molarity
The number of moles of a compound dissolved in enough water to make 1 liter of solution.
Synthesis reactions
These combine two or more reactants to form a larger product.
Decomposition reactions
These split a reactant into one or more smaller products.
Exchange reactions
These couple synthesis and decomposition to trade one or more components of the reactants; as one bond is broken, another is formed.
When a base is added, the concentration of H+ ___________.
Decreases
When an acid is added, the concentration of H+ in the solution __________.
Increases
Macromolecule
A very large molecule usually consisting of repeating subunits.
Polymer
Large molecule formed by the joining together of repeating small molecules (subunits).
Monomer
Subunit of a polymer.
The four major classes of organic molecules:
Carbohydrates, lipids, proteins, and nucleic acids.
Carbohydrates
Monosaccharides; structural component of cell walls; energy source.
Lipids
Subunits are not always similar; some types are important components of cell membranes; energy storage.
Proteins
Amino acids; enzyme catalysts; structural portion of many cell components.
DNA
Deoxyribonucleotides; carrier of genetic information.
RNA
Ribonucleotides; various roles in protein synthesis; catalysis.
Dehydration synthesis
Chemical reaction in which H2O is removed with the result that two molecules are joined together.
Hydrolysis
Chemical reaction in which a molecule is broke down as H2O is added.
Carbohydrates
An organic compound composed of one or more simple sugars.
Monosaccharide
A simple sugar; the basic unit of a carbohydrate.
Disaccharide
Carbohydrate molecule consisting of two monosaccharide molecules.
Polysaccharide
Large molecule composed of many monosaccharide subunits.
Lipid
An organic molecule that is not soluble in water.
Fatty acids
Linear carbon skeletons with a carboxyl group (--COOH) at one end.
Saturated fatty acid
Contain no double bonds between carbon atoms; they have the maximum number of hydrogen atoms.
Unsaturated fatty acid
Contain one or more double bonds between carbon atoms.
Simple lipid
Contain only carbon, hydrogen, and oxygen.
Triglyceride
Molecule consisting of three molecules of the same or different fatty acids bonded to glycerol.
Steroid
Type of lipid with a specific four-membered ring structure.
Polypeptide
Chain of amino acids joined by peptide bonds; also called a protein.
The amino acids in a chain are joined together by covalent bonds called ______.
Peptide bonds
Primary structure
Refers to the sequence of amino acids in a protein.
Secondary structure
Refers to a repeated folding or coiling in a localized region of a protein; the two major arrangements are helices and sheets.
Tertiary structure
The overall three-dimensional shape of a folded protein resulting largely from the interactions of R groups on amino acids.
Quaternary structure
Level of structure or a protein molecule consisting of several polypeptide chains.
Molecular chaperone
Protein that helps other proteins fold properly.
Denature
Disrupt the three-dimensional structure of a protein molecule; separate the complementary strands of DNA.
Adenine and Guanine
Nucleobases that are purines; double-ring structure.
Cytosine, Thymine, and Uracil
Nucleobases that are pyrimidines; single-ring structure.
Capsule
A distinct, thick gelatinous material that surrounds some microorganisms.
Chemotaxis
Movement of a cell toward or away from a certain chemical in the environment.
Flagellum
A type of structure used for cell movement.
Gram-Negative bacteria
Bacteria that have a cell wall characterized by a thin layer of peptidoglycan surrounded by an outer membrane; when Gram stained, these cells are pink.
Gram-Positive bacteria
Bacteria that have a cell wall characterized by a thick layer of peptidoglycan; when Gram stained, these cells are purple.
Lipopolysaccharide (LPS)
Molecule that makes up the outer layer of the outer membrane of Gram-negative bacteria.
Peptidoglycan
A macromolecule that provides strength to the cell wall; it is found only in bacteria.