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106 Terms
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Name the 2 types of glands found in the body.
Endocrine & Exocrine Glands
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What is the difference between Exocrine Glands & Endocrine Glands?
Endocrine glands secrete their products directly into the vascular system without a duct, while exocrine glands secrete their products into a duct.
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Why are endocrine glands also referred to as “ductless” glands?
Because they have lost their connection to a surface since they do not have ducts
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Which one of the 2 glands is most commonly found in the endocrine system?
Most glands of the endocrine system are endocrine glands.
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List examples of Endocrine Glands
pituitary, thyroid, parathyroid, adrenal, and pineal glands
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What are mixed glands of the endocrine system?
glands that secrete hormones and exocrine products
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List examples of Mixed Glands (both endocrine & exocrine)
Pancreas, testes and ovaries
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What is the largest endocrine organ that has both endocrine and exocrine functions?
pancreas
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What is the endocrine organ that has both neuro and endocrine functions?
hypothalamus
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What gland is referred to as the Master Gland of the endocrine system?
anterior pituitary gland
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What gland is referred to as the major metabolic gland?
thyroid gland
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What are the 3 types of Chemical Messengers in the Endocrine system?
hormones, paracrines, & autocrines
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What are Paracrines?
Chemical Messengers that act on other cells within the same tissue.
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List 3 major processes controlled by Hormones?
A. Growth & development
b. Maintaining electrolyte balance
c. Regulating cellular metabolism
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List the 3 types of stimuli needed for hormonal synthesis and release, explain each:
A. Humoral- changing of blood levels of a substance
B. Neural-Nerve fiber stimulation
C. Hormonal- Hormones (tropic hormones) stimulate other endocrine organs to release their hormones
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Which type of stimulus is the most common stimulus causing endocrine glands to go into action and release their hormones?
Hormonal stimulus
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What 2 Endocrine organ/glands are always involved in Hormonal Stimulation?
A. Hypothalamus
B. Anterior Pituitary Gland
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What is the most common Feedback mechanism used by the endocrine system?
Hormones that stimulate other endocrine glands to secrete their hormones. Also referred to as TROPINS.
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What are Tropic hormones? What is another name for it?
Negative Feedback mechanism
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Hormone-sensitive cells that hormones act at are referred to as?
Target cells
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What do chemical mediators of the endocrine system bind to on the Target cells in order to start a change in the cells?
Receptors
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What needs to be present in order for a specific tissue or organ to respond to a hormone?
Appropriate RECEPTORS on the cells of the target tissue or organ must be present.
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What is down-regulation phenomena?
Prolonged excessive exposure to high concentration of hormones causes target cells to lose receptors in response to the hormones, thus down-regulation.
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What are the 2 different chemical structures hormones may be made of?
A. Amino Acid based (Water-soluble)
B. Steroids (Lipid-soluble)
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What is the difference between Water-soluble (amino acid based) and Lipid-soluble (steroid) hormones?
Water-soluble hormones cannot enter Target cells, thus bind to Receptors in the plasma membrane of Target cells and require a 2nd messenger system inside the cell. Steroid hormones can cross the Plasma membrane since they are Lipid-soluble, thus bind to a Receptor inside the Target cell.
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How do protein or amino-acid based hormones exert their effects?
Through intracellular second messengers
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What 2 functions does the Hypothalamus have?
A. Neural B. endocrine
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What do we call the Hypothalamus based on these two functions?
Neuroendocrine Organ
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List 3 functions associated with the Hypothalamus:
A. Control of temperature
B. control of thirst
C. control of Endocrine activity
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What type of Hormones does the Hypothalamus produce and which Gland does it have a direct effect on?
A. Produce: STEERING HORMONES
B. Anterior Pituitary Gland
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Name the 2 Steering Hormones released by the Hypothalamus:
1- A. Corticotropin-Releasing Hormone (CRT)
B. Thyrotropin-Releasing Hormone (TRH)
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Which Steering Hormone released by the Hypothalamus causes the release of Thyroid Stimulating Hormone (TSH) by the Anterior pituitary gland?
Thyrotropin-releasing Hormone (TRH)
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Which Steering Hormone released by the Hypothalamus causes the release of Adrenocorticotropin Hormone (ACTH) by the Anterior pituitary gland?
Corticotropin-releasing Hormone (CRH)
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What endocrine gland is located in the epithalamus that is responsible for our day/night cycle? What hormone does it release?
A. Pineal gland
B. Melatonin
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Does the posterior pituitary gland produce or store hormones?
Store and release. NOT produce
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What is another name for the Pituitary Gland?
Hypophysis
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What 2 hormones is the posterior pituitary gland responsible for storing and releasing?
A. Oxytocin
B. antidiuretic hormone (ADH)
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Which Posterior Pituitary hormone is responsible for Water Balance in the body?
Antidiuretic Hormone (ADH)
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What is the role of Oxytocin during pregnancy? What organ does it have an effect on?
Oxytocin stimulates contraction of the uterine during childbirth. The Uterus!
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Does Oxytocin play a role in milk release? How?
Yes. It causes milk Ejection after labor
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What is the role of Antidiuretic Hormone (ADH)?
Promotes WATER Retention by the Kidneys. (Water Balance)
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Which hormone does Alcohol inhibit the secretion?
Antidiuretic hormone (ADH)
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What hormone is in charge of water balance in the body? What organ releases this hormone?
A. ADH (antidiuretic hormone)
B. Posterior pituitary gland
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What is the Anterior Pituitary gland referred to as in the Endocrine system?
The Master Gland.
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List the 6 hormones of the anterior pituitary? List which are tropic hormones (act on other endocrine glands)
A. Adrenocorticotropic hormone- Tropic hormone
B. Follicle-stimulating hormone (FSH)- Tropic hormone
C. Luteinizing hormone (LH)- Tropic hormone
D.Prolactin E. Growth hormone
F. Thyroid stimulating hormone (TSH)- Tropic hormone
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Which 2 Anterior Pituitary hormones act on Non-endocrine tissue?
A. Prolactin
B. Growth Hormone
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Which 2 Anterior Pituitary hormones are the Gonadotropins?
A. Follicle-Stimulating Hormone (FSH)
B. Luteinizing hormone (LH)
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What gland does Adrenocorticotropic hormone (ACTH) stimulate? What part of the Organ? What Hormone will it stimulate?
Gland: Adrenal Gland
Part: Adrenal Cortex
Hormone: Corticosteriods
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The Antidiuretic hormone is released by the Anterior pituitary gland. True or false?
False. It is released by the posterior pituitary gland
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Which hormone is released towards the end of pregnancy and stimulates Milk production?
Prolactin released by the Anterior Pituitary gland
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What non-endocrine tissue does Prolactin have an effect on?
Mammary glands (breast tissue)
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Name the hormone that targets breast tissue and stimulates milk production during pregnancy? What gland is it secreted from?
A. Prolactin
B. Anterior pituitary gland
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Name the hormone that stimulates bone growth, skeletal muscle tissue and protein synthesis?
Growth hormone
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What does growth hormone stimulate?
A. Growth of long bone
B. skeletal muscle tissue growth
C. Protein synthesis
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What condition occurs due to Hypersecretion of Growth Hormone after long bone growth has ended?
Acromegaly
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What are the 2 parts of the Adrenal Glands? What is each part responsible for producing?
A. Adrenal Cortex, produce Mineralocorticoids & Glucocorticoids
B. Adrenal Medulla, secrete epinephrine & norepinephrine
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What is the most important Mineralocorticoid?
Aldosterone.
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Where is Mineralocorticold produced & released from?
Released by Adrenal Cortex
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What is the most important Glucocorticoid?
Cortisol.
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Where is Glucocorticoid produced & released from?
Released by Adrenal Cortex
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What is the main role of Aldosterone?
Regulates electrolyte balance
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What class of Hormones produced in the Adrenal Cortex plays an important role in Electrolyte balance?
Mineralocortocoids
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What is the most important cation outside the cell?
Na+
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What is the most important cation inside the cell?
K+
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Cortisol is to Glucocorticoids as what is to Mineralocorticoids?
Aldosterone
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What Hormone from the Anterior Pituitary stimulates the release of Corticosteriods by the Adrenal Cortex?
Adrenocorticotropic Hormone (ACTH)
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What are 3 main functions of Glucocorticoids?
A. Help resist long-term stress
B. Suppress inflammation
C. Increase blood glucose levels
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Glucocorticoids help us manage stress by doing what?