BNNS502 Exam 2 Adrenergic & Cholinergic receptors

location of B2 adrenergic receptors

smooth muscle of:

lungs

liver

uterus

location of B1 adrenergic receptors

cardiac muscle

The location of a2 adrenergic receptors is

platelets,

smooth muscle in blood vessels,

sweat glands

Name the 4 different adrenergic receptors

alpha 1

alpha 2

beta 1

beta 2

two types of cholinergic receptors

nicotinic and muscarinic

location of muscarinic cholinergic receptors

P.N.S effectors,

Sweat glands,

Skeletal muscle blood vessels

location of nicotinic cholinergic receptors

cells of adrenal medullae (secretion of adrenaline & noradrenaline),

Neuromuscular end plates of Skeletal muscles (contraction)

cholinergic neurotransmitter

Acetylcholine (ACh)

Muscarinic agonists

Stimulate the parasympathetic response

Muscarnic receptor antagonists

block the parasympathetic response

increased heart rate

sympathetic

1 multiple choice option

decreased blood pressure

parasympathetic

1 multiple choice option

bronchodilation

sympathetic

1 multiple choice option

Decreased GI motility

sympathetic

1 multiple choice option

dilated pupils

sympathetic

1 multiple choice option

Increased secretion of adrenaline

S.N.S

1 multiple choice option

urge to urinate

parasympathetic

1 multiple choice option

SLUDD (Parasympathetic responses)

salivation, lacrimation, urination, digestion, defecation

3 decreases of the parasympathetic system

- decreased heart rate

- decreased diameter of airways

- decreased pupil diameter

The neurotransmitter that activates the cells of liver, causing glycogenolysis is

Adrenaline

The receptors located on the cells of the adrenal medulla are

nicotinic

The drug metoprolol is a β1 antagonist. The effect of this medication is to

Decrease BP

The drug salbutamol is a β2 agonist. The effect of this medication is to

Increase bronchodilation

A muscarinic receptor antagonist drug will

block cholinergic receptors.

Nicotinic receptors are located on

adrenal medullae and skeletal muscles

Name the neurotransmitter or hormone involved with Adrenergic receptors

Adrenaline

Noradrenaline

The location of a1 adrenergic receptors is

smooth muscles in blood vessels and iris

Alpha 1 stimulation causes

vasoconstriction of peripheral blood vessels,

pupil dilation

Alpha 2 stimulation causes:

platelet aggregation, dilation of smooth muscle, increased sweating

Beta 2 stimulation causes

bronchodilation

uterine relaxation

glycogenolysis

Beta 1 stimulation causes

increase heart rate and contractility

Agonist

a molecule that, by binding to a receptor site, stimulates a response

Antagonist

binds to and blocks receptors to prevent a natural neurotransmitter or hormone from stimulating an effect

The effects of a betablocker medication

decreased:

heart rate,

blood pressure,

myocardial contractility,

bronchoconstriction

adrenoreceptor agonist medication

adrenalin

adrenoreceptor agonist effects

enhanced sympathetic activity

increased

adrenalin secretion,

heart rate,

blood pressure,

dilation of

bronchioles

pupils

decreased motility

Would anticholinergic medications be considered agonist or antagonist?

Antagonist

They block receptors for ACh thus inhibiting the effect of ACh

Effects of anticholinergic medications

Decreased skeletal muscle contraction and adrenaline/noradrenaline secretion