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Pathogen
An organism that causes disease
Infection
Contamination or invasion of body tissue by pathogenic organisms
Creutzfeldt-Jakob disease
Rapidly progressive dementia with startle myoclonus
Prions (PrP) change from alpha to beta pleated sheet (resistant to proteases)
Spongiform transformation of gray matter
Mad cow disease
A disease in which prions mutate into deadly pathogens and slowly damage a cow's nervous system.
Barriers to infections
mucous membrane, pH, skin
Innate immunization
Short time, response is immediate, limited diversity, always the same response
Adaptive immunization
Long time, response takes a few days, is specifically to the pathogen that caused, can fight a variety, if second reencounter amplifies responses
Signs of inflamation
redness, heat, swelling, pain, loss of function
Histamine causes
vasodilation and increased capillary permeability
Erythropoiesis
production of red blood cells
Lymphocytes
Natural killer cells
Small lymprocyte
T limphocyte
B lymphocytes
Plasma cells
Leukocytes
Basophil
Neutrophil
Eosinophil
Monocyte
Macrophages
Found within the lymph nodes, they are phagocytes that destroy bacteria, cancer cells, and other foreign matter in the lymphatic stream
Exocytosis
Process by which a cell releases large amounts of material
Phagocytosis is...
a type of endocytosis whereby a cell engulfs a particle in an internal compartment called phagosome
Phagocytic cells of immune system...
Neutrophils
Macrophages
Dentritic cells
Monocytes can mature into...
Macrophages or dencritic cells
Natural killer cells...
killer cells that kill non-self by poking holes in the membrane or inducing apoptosis
MHC is a...
self molecule
Adaptive immunitiy relies on...
special receptors on T and B lymphocytes
Antigens are...
molecules capable of binding to immune components
Immunogens
antigens capable of generating an immune response