[BIO 183i] Quiz 4.2: COVID-19 and Hwang Affair

Veterinary science and theriogenology

What was Hwang Woo-Suk’s background as a researcher from SNU?

Clone first human embryos and extract stem cells

What was Hwang Woo-suk’s claim in their published achievement last February 2004?

Stem Cells

Cell populations with the potential to specialize to any type of somatic cell

Pluripotent

Embryonic stem cells, given their immaturity, is described to be [___]

Pluripotent

Stage of stem cell development wherein a cell is capable of transforming to any body cell type regardless of lineage

Multipotent

Adult stem cells differ from embryonic stem cells because the former is described to be [___]

Multipotent

Stage of stem cell development wherein a cell is described to have a more limited range of differentiation as it is limited to a specific lineage

Somatic Cell Nuclear Transfer

What is the method described by Hwang wherein the nucleus of an adult somatic cell is transferred to an empty oocyte in vitro?

TRUE

T/F: In Hwang’s SCNT, the oocyte is allowed to develop into an embryo (blastocyst) that has pluripotent stem cells that matches the genetic information of a donor.

FALSE

T/F: In Hwang’s SCNT, the oocyte is allowed to develop into an embryo (blastocyst) that has multipotent stem cells that matches the genetic information of a donor.

Clang, Kang Won Rae

South Korean dance duo and individual who was paralyzed from the hips down

Gerard Schatten

American scientist who ceased working with Hwang

Ethical concerns about the egg used for research (coercion of unpaid volunteers, invasive procedure)
Fabricated data in published journal

What were 2 of Schatten’s allegations towards Hwang?

Human cloning was already controversial in itself
Ethical guidelines were overshadowed by impact of his research
Different cultural backgrounds behind ethical practices

Why was support for Hwang firm even amidst speculations of fabrication and problems with egg donation?

Chung Un-Chan

Who was the President of Seoul National University who issued an official statement after the investigation for Hwang?

Establishment of Research Ethics Committee, Reform Research Policies

What were 2 ways inwhich Chung Un-Chain vowed to ascertain that fabrications similar to Hwang’s will not happen again in the future