GI+Meds;Dopamine Antagonists: prochlorperazine
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Last updated 2:18 AM on 11/3/25
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5 Terms
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mechanism of action; prochlorperazine
Blocking the dopamine receptors in the chemoreceptor zone of the brain
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therapeutic use
Prevent emesis r/t chemotherapy, opioids, & post-op recovery
Given PO, IM, rectal or IV
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complications
Extrapyramidal Symptoms (EPS)
Restlessness, anxiety, spasms of face & neck, arms
Hypotension
Sedation
Anticholinergic Effects
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interactions
Same as ondansetron
CNS depressants
Antihypertensives meds
Anticholinergic meds
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Nursing considerations
Increase fluid intake
Increase physical activity
Suck on hard candy or chew gum
Administer laxative
Empty bladder every 4 hours
Photosensitivity
Note 
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