Short-Term Blood Pressure Control (AUTOREGULATION)

Autoregulation is the ______ control of blood flow and blood pressure in the tissues.

local

Tissues ______________ adjust blood flow in response to metabolic needs.

automatically

Autoregulation involves the local release of substances that are _____________ or ________________.

vasodilators, vasoconstrictors

Myogenic response of arterioles (more ______ produces vasoconstriction, etc…)

stretch

What happens during myogenic autoregulation?

smooth muscle fibers in arterioles are stretched due to an increase in blood pressure

Stretch of smooth muscle fibers in arterioles during myogenic autoregulation OPENS mechanically gated _______ channels that causes them to ENTER the smooth muscle resulting in ___________.

cation, depolarization

Depolarization of cations in myogenic autoregulation causes voltage-gated ________ channels to OPEN entering the muscle cells and triggering a smooth muscle ____________.

calcium, contraction

Once smooth muscle contracts during myogenic autoregulation what is the sequence of events that follow?

1) Vasoconstriction 2) smaller arteriole radius 3) increased resistance 4) decreased flow

Myogenic mechanism prevents a sudden increase in blood ___________ and blood ____ being delivered to the organs.

pressure, flow

Place the events of tissue autoregulation in the correct sequence, starting with increased metabolic activity of the tissue.