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Over-the-Counter (OTC) Non-Opioid Analgesics
A class of medications that are available without a prescription and do not contain opioids, used primarily for pain relief.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
A subclass of OTC analgesics that reduce inflammation and pain without the use of steroids.
Generic name: Ibuprofen
Brand name: Advil, Motrin
Pharmacological Subclass: Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
FDA indication: reduce and relieve fever, headache, and pain
Generic Name: Naproxen
Brand name: Aleve
Pharmacological Subclass: Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
FDA indication: reduce and relieve fever, headache, and pain
Generic name: Aspirin
Brand name: Ecotrin, Bayer
Pharmacological Subclass: Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
FDA indication: reduce and relieve fever, headache, and pain
Generic name: Diclofenac
Brand name: Voltaren
Pharmacological Subclass: Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
FDA indication: the relief of pain from osteoarthritis in specific joints, primarily the knees and hands
Generic name: Acetaminophen
Brand name: Tylenol
Pharmacological Subclass: miscellaneous analgesics and an antipyretic
FDA indication: to treat fever and mild to moderate pain.
Brand name: Excedrin Migraine®
Generic Name: Acetaminophen + Aspirin + Caffeine
Pharmacological Subclass/Category: Non-Opioid Analgesic + NSAID + Diuretic
FDA indication: to treat migraines and fever
Topical Analgesic
A class of medications applied to the skin to relieve pain.
Pyrilamine
an ingredient in combination products like Midol Complete and Pamprin Multi-Symptom for relieving symptoms of premenstrual syndrome (PMS). It is used to help with bloating, irritability, and other minor discomforts.
Brand name: Midol Complete®
Generic Name: Acetaminophen, caffeine, and pyrilamine.
Pharmacological Subclass/Category: Non-Opioid Analgesic + Diuretic + Antihistamine
FDA indication: to treat migraine and relieve mild to moderate pain
Brand name: Bengay®, Icy Hot
Generic Name: Camphor + Methyl Salicylate + Menthol
Pharmacological Subclass/Category: Misc. Combination Topical Analgesic
FDA indication: Arthritis and sprains
Topical Anesthetic
A subclass of topical medications used to numb a specific area of the skin.
Postherpetic Neuralgia (PHN)
The most common complication of shingles. A chronic pain condition that develops after a shingles infection (herpes zoster)
Brand name: Lidoderm®
Generic Name: Lidocaine
Pharmacological Subclass/Category: Topical Anesthetic
FDA indication: Topical local anesthetic to skin
and postherpetic neuralgia
Brand name: Neosporin®
Generic Name: Neomycin + Polymyxin B + Bacitracin
Pharmacological Subclass/Category: Topical Antibiotic Ointment
FDA indication: Infection of the skin (burns/cuts) and preparation of bowel for procedure
Brand name: Benadryl
Generic name: Diphenhydramine
Pharmacological Subclass/Category: First-Generation Antihistamines (H1 Antagonists)
FDA indication: Allergy reactions and Common cold
Generic name: Doxylamine
Brand name: Unisom SleepTabs®
Pharmacological Subclass/Category: First-Generation Antihistamines (H1 Antagonists)
FDA indication: Insomnia
Generic Name: Fexofenadine
Brand name: Allegra
Pharmacological Subclass/Category: Second-Generation Antihistamines (H1 Antagonists)
FDA indication: Seasonal allergic rhinitis (hay fever) and Idiopathic urticaria.
Generic name: Cetirizine
Brand name: Zyrtec
Pharmacological Subclass/Category: Second-Generation Antihistamines (H1 Antagonists)
FDA indication: Seasonal allergic rhinitis (hay fever) and Idiopathic urticaria. (may cause mild drowsiness)
Generic name: Loratadine
Brand name: Claritin
Pharmacological Subclass/Category: Second-Generation Antihistamines (H1 Antagonists)
FDA indication: Seasonal allergic rhinitis (hay fever) and Idiopathic urticaria. (non-drowsy)
Generic name: Levocetirizine
Brand name: Xyzal
Pharmacological Subclass/Category: Second-Generation Antihistamines (H1 Antagonists)
FDA indication: Seasonal allergic rhinitis (hay fever) and Idiopathic urticaria.
Generic Name: Fluticasone Propionate
Brand name: Flonase
Pharmacological Subclass/Category: OTC Nasal Corticosteroid
FDA indication: Allergic rhinitis and non-allergic rhinitis.
Generic name: Guaifenesin
Brand name: Mucinex
Pharmacological Subclass/Category: OTC Expectorant
FDA indication: Abnormal sputum
Generic name: Dextromethorphan
Brand name: Delsym
Pharmacological Subclass/Category: OTC Antitussive
FDA indication: Cough
Generic name: Pseudoephedrine
Brand name: Sudafed
Pharmacological Subclass/Category: Oral Decongestant
FDA indication: Nasal congestion