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BIOL 3800.001 with Lisa Welch Spring 2026
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Define Homeostasis
Maintenance of a relatively stable internal environment
Which two systems are the main control systems of the
body?
Nervous and endocrine systems
Which organ system(s) exchanges materials between the
internal and external environments?
Digestive and respiratory
Define Pathophysiology
Study of body functions in a disease state
define diabetes mellitus
condition characterized by abnormally high blood glucose
Response loops begin with a ___.
Stimulus
____ modulate the response loop.
Feedback loops
Define Negative Feedback loops
homeostatic and stabilize the variable by reducing change
Define positive feedback loops
non-homeostatic that amplifies change in the system
Define feedforward control
Allows the body to anticipate control
What is an example of positive feedback loop?
Childbirth, blood clotting, or fruit ripening
What is an example of negative feedback?
Temperature regulation, blood pressure, or osmoregulation
How do you shut off positive feedback?
an outside factor
How do you shutoff negative feedback?
The response loop itself will shut it off
Which of the following is not an example of homeostatic responses?
Sweating increases loss of body fluids, and urination
increases the loss of body fluids.
Which is NOT an example of negative feedback?
uterine contractions during childbirth
Nico is waiting at the start line for the race to begin. His
heart rate is starting to increase, and he is breathing a little
faster. This is an example of
feedforward control
Name the 5 parts of the feedback control system
Stimulus; receptor/sensor; control/integrating center; effector/target; action/response.
Bobby severed a large artery in his leg trying to chop up a block of ice with a knife. After Bobby severed the artery in his leg a cascading event arising from the rough edges of the artery and chemicals released by the damaged cells led to the formation of a clot. What is the sensor?
rough edges of the artery
Bobby severed a large artery in his leg trying to chop up a block of ice with a knife. Because of the large amount of blood Bobby has lost his blood pressure drops. This is detected by baroreceptors in the carotid arteries and the information is relayed to the medulla oblongata in turn the heart is stimulated to beat faster to increase the blood pressure. What is the control?
The medulla oblongata
Bobby severed a large artery in his leg trying to chop up a block of ice with a knife. Because of the large amount of blood Bobby has lost his blood pressure drops. This is detected by baroreceptors in the carotid arteries and the information is relayed to the medulla oblongata in turn the heart is stimulated to beat faster to increase the blood pressure. What is the effector?
The heart
You are taking a hike and spot a venomous snake on the ground a few feet away. Your heart rate becomes elevated and your muscles build tension. This is an example of:
feedforward control
High concentrations of sodium and chloride are found in ___.
Extracellular fluid (ECF)
High concentrations of potassium levels are found in ___.
Intracellular Fluid (ICF)
__ molecules of ___ are removed by the sodium-potassium pump.
3 sodium
The sodium potassium ATPase will pump in __ molecules of __.
2 potassium
Organs included in the circulatory system:
Heart, blood, and blood vessels
Organs included in the digestive system:
Stomach, intestine, liver, and pancreas
Organs included in the endocrine system:
thyroid gland and adrenal gland
Organs included in the immune system:
thymus, spleen, and lymph nodes
Organs included in the musculoskeletal system
skeletal muscles and bone
Organs included in the nervous system:
brain and spinal cord
Organs included in the reproductive system:
ovarties, uterus, and testes
Organs included in the respiratory system:
lungs and airways
Organs included in the urinary system
kidneys and bladder
___ mechanisms maintain the disequilibrium of ECF and ICF to ensure stability and function.
Active Transport
Define Local Control:
Designed to handle small, immediate issues and is restricted to a tissue or cell
Define Reflex control
Deals with larger body-wide adjustments by using the endocrine or nervous system
Define Stimulus
something that removes balance from the system
Define Target
The organ or tissue being told to act
Define output signal
Nerves or hormones that are instructing tissues or hormones to act