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Receptor x
A membrane-bound single-polypeptide receptor that recognizes an external molecule (ligand) and triggers a cellular response; noted to have no alpha helices or beta sheets in this context.
Polypeptide
A chain of amino acids that folds into a functional protein.
Ligand
A molecule that binds to a receptor to elicit a cellular response.
Five-amino-acid sequence (pentapeptide) of receptor x
A short segment within receptor x consisting of five consecutive amino acids used to study sequence effects.
Altered sequence
The pentapeptide sequence of receptor x with two substitutions relative to the normal sequence.