long covid-19

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Last updated 2:17 AM on 12/8/25
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10 Terms

1
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what is long COVID?

WHO definition

  • usually within 3 months from the onset of COVID-19, with symptoms and effects that last for at least 2 months

  • symptoms cannot be explained by alternative diagnosis

  • no minimum symptoms required for diagnosis

  • occurs regardless of disease severity

2
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new NASEM definition

  • LC is an infection-associated chronic condition (IACC) that occurs after SARS-CoV-2 and is present for at least 3 months as a continuous relapsing and remitting or progressive disease that affects one or more organ systems

    • SOB, cough, persistent fatigue, post-exertional malaise

    • can also manifest as single or multiple diagnosable conditions: interstitial lung disease, cardiovascular disease, POTS, chronic fatigue syndrome, fibromyalgia, etc

  • similar to MS in terms of different types

3
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new or worsening preexisting conditions

  • ie. triggers preexisting conditions to become symptomatic that were previously asymptomatic

    • cardiovascular disease (covid can cause blood clots)

    • chronic kidney disease

    • POTS

    • diabetes

    • cognitive impairment

    • etc.

4
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clinical presentation

  • PCC can be characterized as 3 potential categories

    • multi-dimensional (pre-existing condition exacerbated)

    • fluctuating (high level of disability post infection)

    • episodic (moderate)

  • generally has impact on every day functioning → interferes with ability to work, attend school, participate in communities, and engage in ADLs

  • present for prolonged time frames and/or relapse over time

INSERT PIC

<ul><li><p>PCC can be characterized as 3 potential categories </p><ul><li><p>multi-dimensional (pre-existing condition exacerbated) </p></li><li><p>fluctuating (high level of disability post infection)</p></li><li><p>episodic (moderate)</p></li></ul></li><li><p>generally has impact on every day functioning → interferes with ability to work, attend school, participate in communities, and engage in ADLs</p></li><li><p>present for prolonged time frames and/or relapse over time </p></li></ul><p>INSERT PIC</p><p></p>
5
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common symptoms

  • post exertional malaise

  • cognitive impairment

  • depression, anxiety

  • persistent fatigue (MOST COMMON)

  • difficulty concentrating

  • memory changes

  • headaches

  • sleep disturbance

  • SOB, cough

  • problems w/ taste and smell

INSERT PIC

<ul><li><p>post exertional malaise</p></li><li><p>cognitive impairment </p></li><li><p>depression, anxiety </p></li><li><p>persistent fatigue (MOST COMMON)</p></li><li><p>difficulty concentrating</p></li><li><p>memory changes</p></li><li><p>headaches</p></li><li><p>sleep disturbance</p></li><li><p>SOB, cough</p></li><li><p>problems w/ taste and smell</p></li></ul><p>INSERT PIC</p><p></p>
6
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symptoms cont.

  • no clear established link between medical and demographic characteristics and outcomes

  • some causal links noted that may increase risk of PCC:

    • female

    • older, younger

    • minority ethnicity

    • underlying health conditions

    • reinfections

    • pregnant

7
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what is “safe” rehab

  • no standard protocol

  • 4 concepts

    • avoiding acute events & symptom flare-ups → prevents further decline in functional performance

    • personalization

    • facilitating expectations (what does recovery look like?)

    • psychologically supportive → managing client’s expectations/emotions

  • avoid graded exercise therapy → do not want to over exert client

  • establish activity mgmt plan

8
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“safe” rehab signs

pause session, reassess/proceed with caution

  • autonomic dysfunction

  • post exertional malaise

SEE a doctor/terminate session entirely

  • exertional oxygen desaturation (below 92%)

  • cardiac impairment

9
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managing dysautonomia

  • postural orthostatic tachycardia syndrome (POTS) → chronic condition that causes abnormal increase in HR when standing up/sitting up

  • common symptoms

    • difficulty standing still, fatigue, lightheadedness, nausea, brain fog, palpitations, SOB

  • how to treat:

    • exercise

    • lifestyle changes: hydration, adding salt, limiting alcohol

    • compression

      • stockings

      • abdominal binder

    • sleep

      • raising HOB

      • quality sleep

    • pacing

10
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outcome measures

  • post-covid core outcome set (PC-COS)

    • fatigue

    • post-exertion symptoms

    • cognitive functioning

    • mental function

    • pain

    • work/occupational changes

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