For ex: When sperm fertilizes the egg it becomes a zygote. This cell can be specialized in the muscle, skin, and liver
Genes turn off
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4 major tissues in the body
Epithelial
Connective
Muscular
Nervous
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Epithelial Tissue
Lines body cavities that open to the exterior; specialized for \n absorption, secretion and excretion
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Connective Tissue
Specialized to support and cushion the body; the binding tissue, also fights infection
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Muscular Tissue
Specialized for contraction
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Nervous Tissue
Specialized tissue that generates electrical impulses
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Epithelial Tissue features
consists mainly of cells bound together by junctions; little \n extracellular material
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Apical Surface
faces interior or exterior space
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Basal surface
attached to CT layer by the basement membrane
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Avascular
no blood vessels; obtains substances by diffusion
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High rate of cell division in…
ET; cells near basement membrane constantly \n undergoing mitotic division
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Epithelial Tissue functions
1. Physical Protection- Barrier, Abrasions, Dehydration 2. Control Permeability- Selective Absorption (Digestive tract) 3. Provide sensations about environment- Hot, Cold Pressure 4. Produces specialized secretions by forming glands
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2 type of glands in ET
Endocrine and Exocrine
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Endocrine gland
Glands are ductless \n - Hormones are simply secreted into circulation
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Endocrine gland example
thyroid and pituitary
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Exocrine gland
Gland secretions are discharged into ducts \n - Empty onto skin or other epithelial surface
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Exocrine gland
Lacrimal glands, perspiration onto skin, milk in \n mammary glands
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Epithelial Tissue 3 different shapes
squamous, cuboidal, columnar
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Squamous
fried eggs, snake scales look
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Cuboidal
cube-like
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Columnar
Tall columns
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Epithelial 3 cell arrangements
Simple, stratified pseudostratified
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Simple
single layer
delicate, fragile
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Simple ET location
internal protected areas
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Simple ET function
diffusion, absorption, filtration
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Stratified
several layers
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Stratified ET location
external
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Stratified ET function
protection
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Pseudostratified
actually simple, but appears stratified
all cells directly contact the basement membrane
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Simple squamous ET
Most delicate and allows for diffusion/absorption to take place
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Simple squamous ET location
lines outside of intestine and lining of blood vessel
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Simple squamous ET also forms..
serous membrane \n o Lines ventral cavities and organs \n o Pleura (lungs), pericardium (heart) and peritoneum \n (abdominopelvic cavity)
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Stratified squamous ET
Protection against physical/chemical attacks
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Stratified squamous ET location
found in high stress areas
eg: skin (outermost layer) & vagina
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Simple Cuboidal ET
adapted for secretion/absorption
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Simple Cuboidal ET location
Rare; found in sweat glands and mammary glands
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Simple columnar ET Non-ciliated
Secretion/absorption
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Simple columnar ET Non-ciliated location
lining of small intestine
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Simple columnar ET ciliated
protection/movement
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Simple columnar ET ciliated location
respiratory tract and fallopian tubes
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Ciliated pseudostratified columnar ET
Single layer, but looks like more \n - Nuclei are multilayered \n - All cells are still in contact with the basement membrane \n - Its really just ciliated simple columnar in disguise!
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Ciliated pseudostratified columnar ET location
trachea
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Connective Tissue is the…
most widely distributed tissue in the body
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Connective tissue contains specialized cells in and secretes…
1. Extracellular Protein fibers 2. Ground substance
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Ground Substance (CT)
(a clear viscous fluid)
* The extracellular protein fibers and ground substance \n form the matrix.
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Matrix (CT)
a nonliving mixture that exists within the intracellular spaces.
* It can be hard (bone), rigid (cartilage), fluid (blood)
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CT is made up mostly of
matrix
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ET is made up mostly of
cells
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CT is found in underlying..
structures (not on surface structures like ET was).
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CT is highly…
vascularized
ET had no blood supply
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CT functions as a structural framework to…
interconnect and protect, a transport medium, an energy reserve and a defense system against invading microorganisms.
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CT is classified according to 3 things
1. types of fibers 2. types of cells 3. types of matrix
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In CT, what is not vascularized
cartilage
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Types of cells that may be found within connective tissue like…
produce fibers that are found within CT and help to produce parts of the matrix
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Leukocytes
(WBCs) are commonly found in blood, but can also migrate into CTs temporarily
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Leukocytes examples
Macrophages
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Macrophages
phagocytize foreign materials and also signal to \n activate the immune system when stimulated.
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Adipocytes
(fat cells)- store lipids
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Melanocytes
synthesize and store a brown pigment called melanin. Melanin colors the epithelium (epidermis) and CT (dermis) of the skin.
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Mesenchymal
stem cells that respond to injury or infection by dividing and \n then differentiating into different CT cells
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Mast cells
“WBC” contain histamine and heparin which stimulate inflammation
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CT fibers are formed by..
fibroblast
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The types of fibers in CT
Collagen fibers, Reticular Fibers, Elastic Fibers
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Collagen fibers
“Waves”
Most numerous of the 3 fiber types \n o Long, straight and unbranched \n o Composed of the protein, which is VERY STRONG. \n o Appear white when present in large numbers
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Reticular fibers
“Network”
Thinner than collagen fibers \n o Tend to form branched networks
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Elastic Fibers
“Branched and wavy when not stretched”
Have the ability to stretch and then return to original length \n o Composed of the protein elastin
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Elastic fibers are found in:
the air sacs of lungs, dermis of the skin, blood vessels and in between vertebrae
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Reticular fibers are found in and provide..
a strong supporting net that helps to stabilize the organs, BV, nerves and other structures.
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Collagen Fiber are found in:
Tendons and ligaments
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Loose connective tissue
packing material; cushion and stabilize; fill spaces between \n organs; surround and supports other tissues
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Areolar connective tissue is the most…
widely distributed of all the connective tissues.
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Areolar connective tissue
Very loosely organized with an open framework (this allows it to distort without damage)
\n o has very few cells (mostly fibroblasts and macrophages) \n that are not organized in any particular manner.
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Areolar connective tissue function:
Forms a layer that separates the skin from underlying \n structures. This serves to absorb multidirectional shock and permits distortion without damage.
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Areolar connective tissue location:
between epithelial tissue and muscle tissue. Acts similar to \n glue, holding these two structures together.
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Adipose Tissue
Contains mostly adipocytes (fat cells), which have only a small area of cytoplasm and a large fat droplet
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Areolar Tissue
different fibers are scattered throughout the matrix
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Adipose Tissue
very little matrix. The cells are packed closely together and look something like chicken wire.
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Adipose Tissue Function
serves as padding, shock absorber (TG) and filling, as well as an \n insulator and energy preserve
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Adipose Tissue location
can be found under the skin and around certain organs
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These adipocytes can be stimulated by the nervous system to breakdown their lipid contents..
which leads to an increase in body temperature.
eg: Brown fat, found in infants, is different because it is highly vascularized and also contains numerous mitochondria
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Reticular connective tissue
Made primarily of these fibers \n o Will see many dark cells with dark r. fibers scattered throughout
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Reticular connective tissue function
provides a framework to supports cells within
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Reticular connective tissue location
the spleen, liver, lymph nodes and bone marrow
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Dense connective tissues
are dense with protein fibers
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Dense regular connective tissue
Very few cells (a few fibroblasts which produce the many collagen fibers)
Composed of bundles of collagen which are arranged in orderly, parallel rows (looks wavy)
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Dense regular connective tissue function
secures bones during movement
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Dense regular connective tissue location
Tendons, Ligaments, Aponeurosis
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Dense Regular CT
Tendons:
unite skeletal muscle cells; attaches skeletal muscle to bones
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Dense Regular CT
Ligaments:
attach bone to bone
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Dense Regular CT
Aponeurosis:
a flat, sheet-like structure that attaches muscle to bone or bone to bone
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Dense irregular connective tissue
Collagen fibers are not arranged in any particular pattern. The fibers are scattered in various directions.
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Dense irregular connective tissue function
the scattered unordered fashion that the fibers are arranged \n in actually adds to their strength when they are being pulled in different directions.
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Dense irregular connective tissue location
around in joints and also forms a layer around cartilages \n (perichondrium) and around bone (periosteum)
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Elastic Tissue
A dense, regular connective tissue that is dominated by elastic fibers \n o Looks like lasagna when viewed from the side
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Elastic Tissue function
the large amounts of elastic tissue allow it to stretch and then return to its normal size and shape
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Elastic Tissue location
found in the lungs and in some arteries
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Vascular Tissue contains…
Blood Lymph and Cartilage
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Blood
Consists of a liquid matrix called plasma (fluid part of blood) \n o Within the plasma are the suspended elements: