Tissues differentiate during..
Development to carry out specific functions
For ex: When sperm fertilizes the egg it becomes a zygote. This cell can be specialized in the muscle, skin, and liver
Genes turn off
4 major tissues in the body
Epithelial
Connective
Muscular
Nervous
Epithelial Tissue
Lines body cavities that open to the exterior; specialized for \n absorption, secretion and excretion
Connective Tissue
Specialized to support and cushion the body; the binding tissue, also fights infection
Muscular Tissue
Specialized for contraction
Nervous Tissue
Specialized tissue that generates electrical impulses
Epithelial Tissue features
consists mainly of cells bound together by junctions; little \n extracellular material
Apical Surface
faces interior or exterior space
Basal surface
attached to CT layer by the basement membrane
Avascular
no blood vessels; obtains substances by diffusion
High rate of cell division in…
ET; cells near basement membrane constantly \n undergoing mitotic division
Epithelial Tissue functions
Physical Protection- Barrier, Abrasions, Dehydration
Control Permeability- Selective Absorption (Digestive tract)
Provide sensations about environment- Hot, Cold Pressure
Produces specialized secretions by forming glands
2 type of glands in ET
Endocrine and Exocrine
Endocrine gland
Glands are ductless \n - Hormones are simply secreted into circulation
Endocrine gland example
thyroid and pituitary
Exocrine gland
Gland secretions are discharged into ducts \n - Empty onto skin or other epithelial surface
Exocrine gland
Lacrimal glands, perspiration onto skin, milk in \n mammary glands
Epithelial Tissue 3 different shapes
squamous, cuboidal, columnar
Squamous
fried eggs, snake scales look
Cuboidal
cube-like
Columnar
Tall columns
Epithelial 3 cell arrangements
Simple, stratified pseudostratified
Simple
single layer
delicate, fragile
Simple ET location
internal protected areas
Simple ET function
diffusion, absorption, filtration
Stratified
several layers
Stratified ET location
external
Stratified ET function
protection
Pseudostratified
actually simple, but appears stratified
all cells directly contact the basement membrane
Simple squamous ET
Most delicate and allows for diffusion/absorption to take place
Simple squamous ET location
lines outside of intestine and lining of blood vessel
Simple squamous ET also forms..
serous membrane \n o Lines ventral cavities and organs \n o Pleura (lungs), pericardium (heart) and peritoneum \n (abdominopelvic cavity)
Stratified squamous ET
Protection against physical/chemical attacks
Stratified squamous ET location
found in high stress areas
eg: skin (outermost layer) & vagina
Simple Cuboidal ET
adapted for secretion/absorption
Simple Cuboidal ET location
Rare; found in sweat glands and mammary glands
Simple columnar ET Non-ciliated
Secretion/absorption
Simple columnar ET Non-ciliated location
lining of small intestine
Simple columnar ET ciliated
protection/movement
Simple columnar ET ciliated location
respiratory tract and fallopian tubes
Ciliated pseudostratified columnar ET
Single layer, but looks like more \n - Nuclei are multilayered \n - All cells are still in contact with the basement membrane \n - Its really just ciliated simple columnar in disguise!
Ciliated pseudostratified columnar ET location
trachea
Connective Tissue is the…
most widely distributed tissue in the body
Connective tissue contains specialized cells in and secretes…
Extracellular Protein fibers
Ground substance
Ground Substance (CT)
(a clear viscous fluid)
The extracellular protein fibers and ground substance \n form the matrix.
Matrix (CT)
a nonliving mixture that exists within the intracellular spaces.
It can be hard (bone), rigid (cartilage), fluid (blood)
CT is made up mostly of
matrix
ET is made up mostly of
cells
CT is found in underlying..
structures (not on surface structures like ET was).
CT is highly…
vascularized
ET had no blood supply
CT functions as a structural framework to…
interconnect and protect, a transport medium, an energy reserve and a defense system against invading microorganisms.
CT is classified according to 3 things
types of fibers
types of cells
types of matrix
In CT, what is not vascularized
cartilage
Types of cells that may be found within connective tissue like…
Fibroblasts
Leukocytes
Adipocytes
Melanocytes
Mesenchymal
Mast Cell
MMALMF
__M__y __M__others __A__ss __L__ooks __M__f __F__at
Fibroblasts
produce fibers that are found within CT and help to produce parts of the matrix
Leukocytes
(WBCs) are commonly found in blood, but can also migrate into CTs temporarily
Leukocytes examples
Macrophages
Macrophages
phagocytize foreign materials and also signal to \n activate the immune system when stimulated.
Adipocytes
(fat cells)- store lipids
Melanocytes
synthesize and store a brown pigment called melanin. Melanin colors the epithelium (epidermis) and CT (dermis) of the skin.
Mesenchymal
stem cells that respond to injury or infection by dividing and \n then differentiating into different CT cells
Mast cells
“WBC” contain histamine and heparin which stimulate inflammation
CT fibers are formed by..
fibroblast
The types of fibers in CT
Collagen fibers, Reticular Fibers, Elastic Fibers
Collagen fibers
“Waves”
Most numerous of the 3 fiber types \n o Long, straight and unbranched \n o Composed of the protein, which is VERY STRONG. \n o Appear white when present in large numbers
Reticular fibers
“Network”
Thinner than collagen fibers \n o Tend to form branched networks
Elastic Fibers
“Branched and wavy when not stretched”
Have the ability to stretch and then return to original length \n o Composed of the protein elastin
Elastic fibers are found in:
the air sacs of lungs, dermis of the skin, blood vessels and in between vertebrae
Reticular fibers are found in and provide..
a strong supporting net that helps to stabilize the organs, BV, nerves and other structures.
Collagen Fiber are found in:
Tendons and ligaments
Loose connective tissue
packing material; cushion and stabilize; fill spaces between \n organs; surround and supports other tissues
Areolar connective tissue is the most…
widely distributed of all the connective tissues.
Areolar connective tissue
Very loosely organized with an open framework (this allows it to distort without damage)
\n o has very few cells (mostly fibroblasts and macrophages) \n that are not organized in any particular manner.
Areolar connective tissue function:
Forms a layer that separates the skin from underlying \n structures. This serves to absorb multidirectional shock and permits distortion without damage.
Areolar connective tissue location:
between epithelial tissue and muscle tissue. Acts similar to \n glue, holding these two structures together.
Adipose Tissue
Contains mostly adipocytes (fat cells), which have only a small area of cytoplasm and a large fat droplet
Areolar Tissue
different fibers are scattered throughout the matrix
Adipose Tissue
very little matrix. The cells are packed closely together and look something like chicken wire.
Adipose Tissue Function
serves as padding, shock absorber (TG) and filling, as well as an \n insulator and energy preserve
Adipose Tissue location
can be found under the skin and around certain organs
These adipocytes can be stimulated by the nervous system to breakdown their lipid contents..
which leads to an increase in body temperature.
eg: Brown fat, found in infants, is different because it is highly vascularized and also contains numerous mitochondria
Reticular connective tissue
Made primarily of these fibers \n o Will see many dark cells with dark r. fibers scattered throughout
Reticular connective tissue function
provides a framework to supports cells within
Reticular connective tissue location
the spleen, liver, lymph nodes and bone marrow
Dense connective tissues
are dense with protein fibers
Dense regular connective tissue
Very few cells (a few fibroblasts which produce the many collagen fibers)
Composed of bundles of collagen which are arranged in orderly, parallel rows (looks wavy)
Dense regular connective tissue function
secures bones during movement
Dense regular connective tissue location
Tendons, Ligaments, Aponeurosis
Dense Regular CT
Tendons:
unite skeletal muscle cells; attaches skeletal muscle to bones
Dense Regular CT
Ligaments:
attach bone to bone
Dense Regular CT
Aponeurosis:
a flat, sheet-like structure that attaches muscle to bone or bone to bone
Dense irregular connective tissue
Collagen fibers are not arranged in any particular pattern. The fibers are scattered in various directions.
Dense irregular connective tissue function
the scattered unordered fashion that the fibers are arranged \n in actually adds to their strength when they are being pulled in different directions.
Dense irregular connective tissue location
around in joints and also forms a layer around cartilages \n (perichondrium) and around bone (periosteum)
Elastic Tissue
A dense, regular connective tissue that is dominated by elastic fibers \n o Looks like lasagna when viewed from the side
Elastic Tissue function
the large amounts of elastic tissue allow it to stretch and then return to its normal size and shape
Elastic Tissue location
found in the lungs and in some arteries
Vascular Tissue contains…
Blood Lymph and Cartilage
Blood
Consists of a liquid matrix called plasma (fluid part of blood) \n o Within the plasma are the suspended elements:
erthrocytes, leukocytes, platelets
Erythrocytes “RBC”
transports oxygen and carbon dioxide