History of DNA Double Helix

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4 Terms

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Erwin Chargoff

  • 1947

    • Showed that the ratio A to T and C to G was the same across many species

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Maurice Wilkins + Rosalind Franklin

  • 1950’s

  • Produced DNA crystals + x-ray crystallography

  • Suggested DNA double helix

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James Watkins and Francis Crick

  • 1953

  • created model of DNA double helix

    • 2 strands of DNA nts. held together by base pairs

    • Sugar-phosphate backbone exterior

    • BP interior held by hydrogen bonds

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Double alpha helix structure

  • Twisted into alpha double helix structure

  • 1 complete turn = 10 bp = 3.4 nm

  • major + minor groove