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What drives gas exhange?
Diffusion down a partial pressure gradient
What 4 factors affect diffusion (Fick’s Law)?
Surface area, concentration gradient, distance, diffusion coefficiant
Why is countercurrent exchange efficient?
Maintains a continuous diffusion gradient along the entire length of the exchange surface, allowing for maximal oxygen uptake
Why is gas exchange harder in water?
O2 diffuses slower + less dissolved O2
What does the Bohr effect do?
It says that low pH results in hemoglobin releasing O2
What is the difference between osmoconformers and osmoregulators?
Conformers match environment; regulators control internal balance
What happens in a hypotonic solution?
Water enters the cell resulting in swelling
What happens in a hypertonic solution?
Water leaves the cell, resulting in the cell shriveling.
Most toxic nitrogen waste
Ammonia
Why do bird use uric acid?
It helps them save water
What are the 4 steps of urine formation?
Filtration, reabsorption, secretion, excretion
What causes muscle contraction?
Actin + myosin sliding (requires ATP)
Why does rigor mortis happen?
No ATP → myosin stuck to actin
Slow vs fast twitch?
Slow = endurance; Fast = strength/power
Where is sperm produced?
Seminiferous tubules
What hormone triggers ovulation?
LH surge
What does hCG do?
Maintains corpus luteum (pregnancy signal)
How does birth control work?
Prevents LH surge → no ovulation
A fish gill system switches from countercurrent to concurrent flow. What happens to oxygen uptake?
It decreases because equilibrium is reached quickly, stopping diffusion
At high altitude, why does oxygen loading into hemoglobin decrease?
Lower atmospheric pressure → lower O₂ partial pressure gradient
Increasing which variable would MOST increase diffusion rate?
Increasing surface area
Why is hypoxia more likely in warm water?
Warm water holds less dissolved oxygen
If diffusion distance doubles, what happens to diffusion rate?
It decreases (inverse relationship)
Why is the tracheal system in insects so efficient?
Oxygen is delivered directly to cells without circulatory system
Why don’t birds experience “dead space” like mammals?
Unidirectional airflow keeps fresh air continuously moving
A cell placed in a hypertonic solution will:
Lose water and shrink
Why do freshwater fish produce large amounts of dilute urine?
Water constantly enters their bodies via osmosis
Which nitrogen waste requires the MOST water to excrete?
Ammonia
Why do birds use uric acid instead of urea?
Conserves water and is safer for egg development
Where does filtration occur in the nephron?
Glomerulus → Bowman’s capsule
What is the main function of the Loop of Henle?
Creates concentration gradient to concentrate urine
If ADH levels increase, urine will become:
More concentrated
What happens if ADH is NOT present?
Collecting duct is impermeable to water → dilute urine
Which process moves glucose back into the blood?
Reabsorption
Put in order: filtration, excretion, secretion, reabsorption
Filtration → Reabsorption → Secretion → Excretion
What directly causes the power stroke?
Release of ADP + Pi from myosin
What happens immediately after ATP binds to myosin?
Myosin detaches from actin
What exposes myosin-binding sites on actin?
Calcium binding → moves tropomyosin
If calcium cannot be released, what happens?
No contraction occurs
What happens to the H-zone during contraction?
It decreases or disappears
Why does rigor mortis occur?
No ATP → myosin cannot detach
Maximum force occurs when:
Optimal overlap between actin and myosin
Which fiber type has the most mitochondria?
Slow-twitch
A sprinter relies primarily on which ATP source?
Glycolysis (anaerobic)
Which fiber type appears red and why?
Slow-twitch due to high myoglobin
What stage is released during ovulation?
Secondary oocyte
What directly triggers ovulation?
LH surge
Why does estrogen switch to positive feedback before ovulation?
To trigger LH surge
What maintains the corpus luteum during pregnancy?
hCG
If hCG is NOT produced, what happens?
Corpus luteum degenerates → menstruation
What is the role of progesterone?
Maintain uterine lining
Most of the semen volume comes from
Accessory glands (not sperm)
Where are androgens produced?
Leydig cells
Birth control pills prevent ovulation by:
Preventing LH surge through negative feedback
A mutation reduces hemoglobin affinity for oxygen. What happens?
More oxygen is released to tissues
Why is urea less toxic than ammonia?
It requires less water and is chemically more stable
If the Loop of Henle is damaged, what happens?
Urine cannot be concentrated effectively
During intense exercise, why does oxygen unloading increase?
Lower pH (Bohr effect)
Why are slow-twitch fibers fatigue-resistant?
They rely on aerobic respiration and have more mitochondria
What happens in the proximal convoluted tubule?
Reabsorption of glucose, amino acids, water and ions
A patient has damage to their proximal convoluted tubule. Which of the following is MOST likely to occur?
Increased glucose in the urine