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jaw infection and cancer
can look very similar radiographically
both can have poorly-defined margins
both can be widespread
both can look irregular
pathogenesis
apical periodontitis is not the same thing as periodontal disease
caries/trauma cause necrotic pulp and apical periodontitis
acute โ periapical abscess that becomes osteomyelitis
chronic โ periapical granuloma that becomes periapical cyst
osteomyelitis
infection invades bone
body tries to โwall offโ dental infection
if body does not succeed, osteomyelitis can occur
mixed radiolucencies/radiopacities in irregular manner
enlarged tonsils, indicating presence of infection

periosteal reaction
reactive process in which new bone is deposited within periosteum for bone expansion
consider osteomyelitis, osteosarcoma (cancer), langerhans cell histiocytosis (cancer)

fistula
path of drainage for pus (neutrophils)
referred as sinus tract, fistulous tract, abscess
can have presence of periosteal reaction

osteonecrosis
dead bone caused by osteomyelitis
with H&E โ nuclei are absent from lacunae in bone
bacteria seen all over surface of bone
caused by severe physical trauma, high amounts of radiation, certain medications (bisphosphonates)

pericoronitis
inflammation around the crown
commonly seen with wisdom teeth
diagnosis made clinically, but can see radiographic evidence similar to periodontitis
dense, reactive bone formation may present around follicle
