BIOL Resp. Lecture March 3

what happens when pH drops or temp rises?

• there is more O2 released from hemoglobin

• curve shifts to the right

• skeletal generates heat = more O2 is released

what happens when pH rises or temp drops

• less O2 released

• curve shifts to the right

Bohr effect

the effect of pH on the hemoglobin saturation curve

what does the build up of CO2 do in the blood? (not done)

• CO2 diffuses into the RBC

fetal hemoglobin

fetal Hb binds more O2

myoglobin

O2 storing protein in skeletal muscle

The effects of BPG

changes hemoglobins shape to help hemoglobin bind to O2 properly (makes sure that it doesn’t bind to O2 too tightly. Without it, O2 wouldn’t be able to be given up)

CO2 transport (3 ways)

• 70% converted to carbonic acid

• 23% bound to protein portion of Hb

• 7% dissolved in plasma

dorsal respiratory group

quiet and forced breathing

what does the dorsal respiratory group stimulate?

diaphragm and external intercostal muscles