MASTER cardiac drug adverse effects

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34 Terms

1
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aliskiren

diarrhea

2
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ace inhibitors

first dose hypotension, cough, hyperkalemia, angioedema, and neutropenia

3
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arbs

angioedema, teratogenic, kidney injury, hypotension, and dizziness

4
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aldosterone antagonists

hyperkalemia, hyponatremia, and gynecomastia

5
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verapamil

constipation

6
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diltiazem (5)

constipation, dizziness, flushing, HA, and ankle/foot edema

7
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nifedipine

reflex tachycardia

8
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hydralazine

reflex tachycardia, increased BV, and lupus-like syndrome

9
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minoxidil

reflex tachycardia, increased BV, hypertrichosis, pericardial effusion, thrombocytopenia, and SJS

10
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sodium nitroprusside (2)

hypotension and cyanide poisoning

11
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digoxin

dysrhythmias, N/V/anorexia, and fatigue

12
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procainamide

lupus-like syndrome

13
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flecainide (2)

prolonged PR interval and widened QRS complex

14
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propafenone (2)

prolonged PR interval and widened QRS complex

15
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beta blockers (7)

HF, AV block, sinus arrest, hypotension, bradycardia, decreased CO, and bronchospasms

16
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potassium channel blockers

lung damage, cardio/thyroid/liver toxicity, and blindness

17
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adenosine (5)

(these are <1 min) sinus bradycardia, dyspnea, hypotension, facial flushing, and chest discomfort

18
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statins

myopathy and rhabdomyolysis

19
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nicotinic acid/niacin

flushing

20
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colesevelam

constipation

21
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fibrates

GI disturbances and rash

22
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nitroglycerin (3)

HA, orthostatic hypotension, and reflex tachycardia

23
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heparin

heparin-induced thrombocytopenia

24
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warfarin

teratogenic

25
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aspirin (4)

GI bleed, hemorrhagic stroke, tinnitus, and hearing loss

26
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clopidogrel

thrombotic thrombocytopenic purpura

27
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alteplase

intracranial hemorrhage

28
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clonidine (2)

dry mouth and drowsiness/sedation

29
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methyldopa (2)

dry mouth and drowsiness/sedation

30
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ranolazine (4)

constipation, dizziness, nausea, and HA

31
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-parin (2)

bleeding and thrombocytopenia

32
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dabigatran etexilate (2)

bleeding and GI disturbances

33
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rivaroxaban (2)

bleeding and spinal/epidural hematoma

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abciximab

major bleeding risk