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aliskiren
diarrhea
ace inhibitors
first dose hypotension, cough, hyperkalemia, angioedema, and neutropenia
arbs
angioedema, teratogenic, kidney injury, hypotension, and dizziness
aldosterone antagonists
hyperkalemia, hyponatremia, and gynecomastia
verapamil
constipation
diltiazem (5)
constipation, dizziness, flushing, HA, and ankle/foot edema
nifedipine
reflex tachycardia
hydralazine
reflex tachycardia, increased BV, and lupus-like syndrome
minoxidil
reflex tachycardia, increased BV, hypertrichosis, pericardial effusion, thrombocytopenia, and SJS
sodium nitroprusside (2)
hypotension and cyanide poisoning
digoxin
dysrhythmias, N/V/anorexia, and fatigue
procainamide
lupus-like syndrome
flecainide (2)
prolonged PR interval and widened QRS complex
propafenone (2)
prolonged PR interval and widened QRS complex
beta blockers (7)
HF, AV block, sinus arrest, hypotension, bradycardia, decreased CO, and bronchospasms
potassium channel blockers
lung damage, cardio/thyroid/liver toxicity, and blindness
adenosine (5)
(these are <1 min) sinus bradycardia, dyspnea, hypotension, facial flushing, and chest discomfort
statins
myopathy and rhabdomyolysis
nicotinic acid/niacin
flushing
colesevelam
constipation
fibrates
GI disturbances and rash
nitroglycerin (3)
HA, orthostatic hypotension, and reflex tachycardia
heparin
heparin-induced thrombocytopenia
warfarin
teratogenic
aspirin (4)
GI bleed, hemorrhagic stroke, tinnitus, and hearing loss
clopidogrel
thrombotic thrombocytopenic purpura
alteplase
intracranial hemorrhage
clonidine (2)
dry mouth and drowsiness/sedation
methyldopa (2)
dry mouth and drowsiness/sedation
ranolazine (4)
constipation, dizziness, nausea, and HA
-parin (2)
bleeding and thrombocytopenia
dabigatran etexilate (2)
bleeding and GI disturbances
rivaroxaban (2)
bleeding and spinal/epidural hematoma
abciximab
major bleeding risk