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Helicase
Unwinds the DNA, cutting the hydrogen bonds, creating a Replication Fork
SSBP
Binds to the open DNA Strands keeping the sides from re-annealing(re-joining)
DNA Pol 3
Adds DNA nucleotides in a 5’ to 3’ direction at the end of the Primer
DNA Pol 1
Removes the RNA Primer and replaces it with DNA nucleotides, fixes any mutations it finds
DNA Ligase
Joins Okazaki Fragments by building a covalent bond between the nucleotides on the lagging strand
Topoi