Cell Communication

Part of chapter 9

Reception

Step 1 of signal being converted into a response, a signaling molecule binds to a receptor protein

Transduction

Step 2: The signal is converted into a form that can produce a cellular response

Response

Step 3: The transduced signal triggers a cellular response

Ligand

A chemical message/signal molecule

Hydrophilic Ligands

Bind to plasma membrane receptors (transmembrane

Small or Hydrophobic Ligands

Can pass through the membrane and bind to intracellular receptors

G-Protein Coupled Receptor (GCPR)

G-protein binds to the energy-rich molecule GTP (similar to ATP)

Receptor Tyrosine Kinases (RTKs)

Membrane receptors that transfer phosphate groups from ATP to another protein, can trigger multiple signal transduction pathways at the same time

cAMP

Quorum