Anaerobic Cellular Respiration
Fermentation
- Anaerobic
- Found in nearly all cells (plants, animal, bacteria)
- Used alongside aerobic cell respiration in most cells
- Different types of fermentation variations depending on cells
- Happens in the cytoplasm
- Essentially just: glycolysis plus an extra step (NAD+ regeneration)
- Doesn’t completely break down glucose like aerobic resp.
- Doesn’t use oxygen = less dangerous ( less risk of free radicals)
ATP Production
- Only produces 2 molecules of ATP thru glycolysis
- Not sustainable for most cells
- Aerobic respiration produces 36 molecules of ATP
Two Types
- The product defines the type
Alcoholic Fermentation
- Converts glucose into ethyl alcohol
- Glycolysis runs. Produces: 2 ATP, 2 NADH, 2 pyruvates
- Pyruvate loses carbon as CO₂, remaining fragment of pyruvate = acetaldehyde
- Acetaldehyde accepts H+ and electrons from NADH = ethanol
Uses: food (bread, wine, beer, vinegar), medicines (antiseptics, disinfectants), biofuels

Lactate Fermentation
- Converts glucose into lactate
- AKA lactic acid fermentation
- Glycolysis runs. Produces: 2 ATP, 2 NADH, 2 pyruvates
- NADH donates electrons and H+ to pyruvate = lactate
- Nothing is being broken down, no C lost= no CO₂ produced
- Uses: cheese,yogurts, kimchi, pickles. Soy sauce, miso paste, sausage, bacon (curing meats)
- Also used in animal skeletal muscles
Intense exercise depletes O₂ in muscles, anaerobic fermentation takes over and makes small amounts of ATP. For quick bursts of activity, doesn’t support prolonged exertion since little ATP us made
