lipogenesis

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23 Terms

1
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adipose

Cattle, Sheep, and Pigs → Major site of fat synthesis is ___ tissue

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liver

Birds (Poultry) → Major site of fat synthesis is the ___.

3
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triglycerides

Extracting fatty acids from circulating ____ (via lipoprotein lipase).

4
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De novo

____ synthesis of fatty acids using glucose as a precursor.

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chylomicrons

Dietary fat contributes fatty acids through _____ (in monogastrics)

6
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breaks

Located on capillary walls, LPL ____ down circulating triglycerides so fatty acids can be absorbed by adipose tissue.

7
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limiting

Rate-___ enzyme in the uptake of fatty acids from the blood.

8
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dietary

Monogastric animals (e.g., pigs) → Fatty acid composition in adipose tissue closely reflects ___ fat.

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softer

Feeding highly unsaturated fats results in ___ body fat with lower melting points.

10
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directly

Non-Ruminants (e.g., pigs) → Dietary fat is ___ absorbed and influences body fat composition.

11
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Ruminants

____ (e.g., cattle, sheep) → Dietary fat is modified by rumen microbes through biohydrogenation before absorption, reducing the impact of dietary fatty acid composition on body fat.

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Glucose

Non-Ruminants____ is the primary substrate for fatty acid synthesis

13
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Acetate

Ruminants___ (a volatile fatty acid from rumen fermentation) is the primary substrate.

14
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short

Other
____-chain fatty acids (propionate, butyrate) contribute to a lesser extent.

15
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limited

Ruminants have ____ glucose availability because microbial fermentation converts most dietary carbohydrates into volatile fatty acids (VFAs) rather than glucose.

16
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spared

Glucose is ___ for vital tissues like the brain, red blood cells, and mammary glands

17
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activity

Non-Ruminants have higher ___ of lipogenic enzymes, allowing them to synthesize fatty acids from glucose.

18
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lack

Ruminants ___ key enzymes (e.g., glucokinase, citrate cleavage enzyme, malic enzyme) in the liver and adipose tissue, making acetate the dominant lipogenic substrate.

19
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Young

___ ruminants (pre-rumen development) can synthesize fat from glucose, but this ability diminishes as the rumen matures.

20
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directly

In pigs and poultry, dietary fat composition ___ influences carcass fat quality.

21
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saturated

In cattle and sheep, fat composition is less affected by diet due to microbial biohydrogenation, making carcass fat more ______.

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less

Feeding high-fat diets to ruminants is ___ effective in altering body fat composition compared to non-ruminants.

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rumen

In young ruminants, glucose can still be used for fat synthesis before full ___ development.