Cardiac Drugs 2130

What type of channel does Amiodarone block?

Potassium Channel

What is one indication for using Amiodarone?

V-Fib

V-tach

What is an indication for Amiodarone in stable complex cases?

Uncontrolled by adenosine

What is an indication for Amiodarone in atrial conditions?

A-fib/A-Flut

What is the dosage of Amiodarone for IV/IO administration?

300 mg

What is the ineffective dosage of Amiodarone after the initial dose?

150 mg

What is the action of Epinephrine?

Alpha Beta Stim, Vasoconstriction

What are the indications for using Epinephrine?

Cardiac arrest, Bradycardia, Anaphylaxis, Bronchoconstriction

What is the standard dose of Epinephrine for IVP/IO?

1mg every 3-5 minutes for Cardiac Arrest

What is the infusion dose of Epinephrine in 250 or 500cc?

2-10 mcg/min until heart rate increases to 60

lidocaine actions

Sodium channel blocker

changes slope of phase 1

Shortens refractory period

V Fib threshold

Lidocaine Indication

Alternative therapy in

V-Fib/V-Tach

Stable V-Tach

Lidocaine dosage

1-1.5mg/kg IVP/IO

repeat 0.5-0.75 mg/kg every 5-10 minutes

maintenance: 2-4 mg a min

Magnesium Sulfate actions

Electrolyte for nerve transmission

Mag sulfate Indications

Torsades

V-tach with long QT

Pulsless V-fib/Vtach

Mag sulfate Dosage

1-2 gm in 10 ml IV/IO Bolus

maintenance .5-1gm/hr

Adenosine Actions

SA/Av node conduction

6-8 seconds

Adenosine indications

Stable

Supraventricular

Tachycardia

Adenosine dosage

6mg IV/IO push

Second dosage 12mg total

20ml flush

Sotalol Action

Beta blocker

potassium channel blocker

sotalol indication

v tach

ventricular arrythmias

Sotalol Dosage

100 mg 1.5mg/kg over 5 minutes

Procainamide Action

Prolongation of refractory period of atria and ventricles, blocks sodium from entering potassium channels

Procainamide Indication Primary

Stable V-Tach

Procainamide Indication Secondary and other

A Fib/Futter, w/ WPW

SVT uncontrolled by adenosine

Procainamide Dosage

20-30 mg/min IV/IO Piggyback drip

Max 17mg/kg

Ectopy resolve

Hypotension occurs

QRS widens by 50%

Diltiazem action

Calcium Channel blocker

Sa/Av node conduction

Vasodilation

Diltiazem Indication

Stable SVT not corrected by adenosine

Stable Junction Tach

Stable A-Fib/A-Tach

Control rate not rythem

Diltiazem Dosage

.25 mg/kg IV/IO slow push over 2 minutes

repeat at .35 mg/kg 15 minutes after

Verapamil Action

-Calcium channel blocker

Vasodilator

Verapamil Indication

Stable SVT not corrected by Adenosine

Junction tach

Afib Atach

Verapamil dosage

2.5-5mg SLOW IV

Isoproterenol Action

Beta agonist

Isoproterenol Indication

Stable torsades

Hemodynamically significant bradycardia

beta blocker overdose

Isoproterenol Dosage

Iv/IO drip 1mg to 250 ml d5w 2-10 mcg/min

Atropine sulfate action

Blocks action of parasympathetic system in the SA and AV node

Atropine sulfate indication

Hemodynamically significant bradycardia

Type one and 2 type 1 block

Atropine sulfate dosage

1.0 mg fast IVP

Calcium Chloride action

Electrolyte for conduction of nerve impulses in cells

Calcium Chloride indication

Hyperkalemia, calcium channel blocker OD

Mag administration issue

Calcium chloride dosage

8-16mg/kg SLOW IVP

Dobutamine action

Beta 1 stimulation HR FORCE VASODILATION

Dobutamine Indication

Pulmonary congestion CHF low cardiac output

Dobutamine dosage

IV/IO drip 2-20mcg/kg/min

Prepare infusion of 500mg/250cc

Dopamine Action

Alpha and beta stimulation

HR FORCE vasoconstriction

Renal mesenteric blood flow

Dopamine Indication

Cardiogenic shock bradycardia

non hypovolemic shock

Dopamine dosage

IV/IO drip

2-5 renal artery dilation

5-15mcg/kg/min Beta

15-20 mcg/kg/min Alpha and beta

Furosemide action

Reabsorption in kidneys drops urine output

Furosemide indication

Left heart failure with PE

Atelectasis

Furosemide dosage

.5-1.0mg/kg IV/IO push slow ov er 2 minutes

Midazolam/Versed action

Sedative effects vasodilator

Midazolam/Versed indication

Sedation prior to cardioversion pacing

Midazolam/Versed dosage

1-2.5mg slow IVP

Nitro action

Relaxes vascular smooth muscles

vasodilation myocardial oxygen demand

Nitro indication

Chest pain, ACS, Angina, MI, CHF

Nitro dose

SL dose= 0.3 or 0.4mg tablet every 5 minutes 3 times

Paste=1-2 inches every 8 hours

IV/IO 10-20mcg/min

Norepinephrine action

Primary stimulates alpha receptors vasoconstriction

Norepinephrine indication

Vasodilatory shock after fluid resuscitation in septic this is preferred vasopressor after IV fluids

Norepinephrine dosage

0.5-12mcg/min titrate to BP