BB2 and H Blood Group Systems and Secretor Status Review

These flashcards cover key concepts, definitions, and facts related to ABO and H blood group systems and secretor status based on lecture notes.

What are the four main blood groups in the ABO system?

Group A, Group B, Group AB, Group O.

Which blood group has no antigens present on the red blood cells?

Group O.

What type of antibodies are present in Group A plasma?

Anti-B antibodies.

Who is considered the universal donor?

Group O, because they have no A or B antigens.

Who is considered the universal recipient?

Group AB, due to lack of circulating ABO antibodies.

What should be preferred for RBC transfusions?

ABO-identical units or ABO-compatible units.

What is a key indicator of ABO discrepancies?

When forward typing does not agree with reverse typing.

What is polyagglutination?

A hidden antigen on RBCs is exposed due to bacterial infection or genetic mutation, reacting with most human sera.

How are weak or missing antigens in ABO subgroups typically identified?

Through weak or negative agglutination in testing.

What is the Bombay phenotype characterized by?

Lack of the H antigen, resulting in phenotype hh.

What precautions should be taken when testing for ABO discrepancies?

Repeat testing to rule out technical errors and check patient diagnosis.

What are cold alloantibodies?

Antibodies that react at room temperature or below, potentially complicating blood typing.

What happens in mixed-field reactions?

Both agglutinated and unagglutinated cells are present, often indicating transfusion of incompatible blood.