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Gas exchange
Supplies oxygen (O2) to the body and removes carbon dioxide, a waste product of cellular respiration
Voice production
The larynx (voice box) houses vocal cords that vibrate to produce sound when air flows through
Regulation of blood Ph
By adjusting breathing rate and CO2 levels, the respiratory system helps maintain the body’s acid-base balance
Olfaction
Airborne molecules stimulate sensory receptors in the nasal cavity, contributing to the sense of smell
Protection
Mucus traps microbes and debris; cilia help move them out of the respiratory tract; coughing expels irritants
Pathway of breathing
Nasal or oral cavity → pharynx → larynx →trachea → bronchi → bronchioles → alveoli
What does the nasal cavity do
Filters, moistens, and warms air
What does the pharynx do
shared passage or food and air
What does larynx do
Routes air to the trachea and food to the esophagus; also involved in sound and production
What does the trachea do
held open by C=shaped cartilage rings
What does the bronchi do
branch into each lung and divide into smaller bronchioles
Alveoli
are tiny, balloon-like air sacs located at the ends of bronchioles and surrounded by a dense network of pulmonary capillaries, brinhing air and blood into close contact
What is the function of alveoli
This is the primary site of gas exchange in the lungs. Oxygen diffuses from the alveoli into the blood, and carbon dioxide diffuses from the blood into the alveoli to be exhaled
What is the structure of alveoli
Thin walls and large surface area and make gas exchange highly efficient
External reparation
The exchange of gases between the alveoli of the lungs and the pulmonary capillaries. Oxygen moves from air sacs into blood; carbon dioxide moves from blood into alveolar air
Internal respiration
The exchange of gas between systemic capillaries and body tissues. Oxygen diffuses into tissues; carbon dioxide diffuses into the blood
O2 concentration is higher in the alveoli and blood than in body tissues
So O2 diffuses into tissues
CO2 concentration is higher in tissues than in blood
So, CO2 diffuses into the blood, then into alveoli to be exhaled
Oxygen (02) transport
98% of 02 binds to hemoglobin in red blood cells, forming oxyhemoglobin. 2% dissolves directly into plasma
Carbon dioxide (CO2) transport
70% is transported as bicarbonate ions (HCO3-) in plasma, formed via the reaction; CO₂ + H₂O ⇌ H₂CO₃ ⇌ H⁺ + HCO₃⁻
20% binds to hemoglobin as carbaminohemoglobin and 10% dissolves directly in plasma
The bicarbonate buffering system helps regulate blood pH:
When CO2 increases, more carbonic acid forms, releasing H+ ions and lowering pH (more acidic)
When CO2 decreases, H+ ions are removed, raising pH (more basic)
Control of respiration
The medulla oblongata in the brainstem controls the basic rhythm of breathing by sending impulses to the diaphragm and intercostal muscles, every 4-5 seconds. Chemoreceptors in the medulla, aortic bodies, and carotid bodies monitor CO2,H+, and O2 levels
Aortic & Carotid bodies location
Near the arch of the aorta (aortic bodies) and at the bifurcation of the carotid arteries in the neck (carotid bodies)
Aortic & Carotid bodies function
Detect changes in blood oxygen concentration. When oxygen levels fall, they signal the respiratory center to increase ventilation
What is the function of the pharynx
Serves as a common passage for both food (to the esophagus) and air (to the larynx)
What is the function of the larynx
Also known as the “voice box”, it routes air to the lungs and food to the esophagus and contains vocal cords for sound production
What is the function of the epiglottis
A flap of tissue that covers the trachea during swallowing, preventing food from entering the airway
What is the function of bronchioles
The smallest conducting airways; they control airway resistance and direct air to the alveoli for gas exchange