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6 Terms

1
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tgfb

more CDKi’s (p21/p15), less c-myc, induce apoptosis

MMPs/snail, slug, induce EMT

2
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wnt/beta-catenin

B-C: myc, snail, slug, cyclin D1

no B-C: rho and rac - actin. inhibs B-C.

3
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hedgehog

cyclin Ds, VEGF, snail

4
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notch

myc, cyclin D1, bcl-2

5
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erk/mapk

myc (cyclin D1), nrf2 (bcl2), elk 1 (fos, jun)

6
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myb

mmp9, bcl2/xl, cyclin E1, myc