5.13 Effects of Drug Use and Tolerance

These flashcards cover key concepts related to drug use, tolerance, and physiological responses as discussed in the lecture.

Tolerance

The need for an ever-increasing dosage of a drug to achieve the same psychological effect.

Metabolic and Cellular Tolerance

Biological changes in the body that increase efficiency in removing drugs from the system.

Down Regulation of Receptors

The process where neurons decrease the number of receptors in response to prolonged drug use.

Psychological Dependence

The condition in which individuals continue drug use due to the need to alleviate negative emotions or stress.

Anticipatory Drug Response

The physiological changes that prepare the body for the expected effects of a drug.

Context Dependent Overdoses

Increased likelihood of overdose when drugs are taken in unfamiliar environments.

Dopamine

A neurotransmitter involved in reward and pleasure pathways in the brain.

Smooth Endoplasmic Reticulum

An organelle that helps filter toxins out of the cell, particularly increased in alcoholics.

Withdrawal Symptoms

Negative physical and psychological effects experienced when stopping a drug.

Conditioning

A learning process in which an environmental cue paired with drug use influences behavior and response.