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What is compact bone composed of?
Osteons
What is spongy bone composed of?
Trabeculae
Where is spongy bone located in bones?
Inner part
Functions of Skeletal System
support, protection, movement, storage, blood cell production
Where is compact bone located in bones?
External layer
Periosteum
A dense fibrous membrane covering the surface of bones (except at their extremities) and serving as an attachment for tendons and muscles.
Bone cells
osteocytes
extracellular matrix
extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells.
skeletal muscle
responsible for voluntary movement
Cardiac muscle
Involuntary muscle tissue found only in the heart, striated
Smooth muscle
involuntary muscle found in internal organs
Muscle tissue
A body tissue that contracts or shortens, making body parts move. Able to respond to stimulus
Muscle Cell
muscle fibers. long and slender and contains fibers that aid in contracting and relaxing
Structure of muscle organ
A muscle organ is composed of multiple muscle fibers bundled together within connective tissue layers
antagonistic pairs
muscles that serve opposite functions; when one muscle contracts, the other lengthens
Structure of Tendons
connective tissue, extending from muscle fascicle +fiber
Muscle polymer
myofibril
Muscle monomer
sacromere
Myofibrils
protein structures that make up muscle fibers. organelles within muscle fibers that are responsible for muscle contraction
myofilaments
The muscle contractile proteins, thin filaments actin and thick filaments myosin, of muscle cells
Sliding filament model
Idea of how a muscle fiber receives impulses from a nerve and causes contraction
CNS (central nervous system)
brain and spinal cord
Structures of neurons
cell body, dendrites, axon
Glial cell functions
help neurons regulate nutrient/ion concentration. To surround neurons and hold them in place. to insulate one neuron from another
Types of neurons
sensory, motor, interneurons
sensory neurons
neurons that carry incoming information from the sensory receptors to the brain and spinal cord
motor neurons
neurons that carry outgoing information from the brain and spinal cord to the muscles and glands
interneurons
neurons within the brain and spinal cord that communicate internally and intervene between the sensory inputs and motor outputs
Myelin sheath
Produces cerebrospinal fluid, scavenge dead cells, pathogen in brain, structural support for synapse, stimulate nerve growth.
Nerve Signal
electrical impulses that travel through nerve cells, or neurons, to transmit information
What Ions are crucial for a neuron to function?
K+, Na+, Cl-
State of neuron at rest
-70 mv
Na+/K+ pump
Active transporter that moves three Na+ out of a cell and two K+ into the cell against their respective concentration gradients.
More__ on the outside, more ___ on the inside
More Na+ on the outside, more K+ on the inside
Neuron function
sensory, motor, association
How does a electrical signal start?
when the membrane potential of a cell changes:
1. Inside of the cell used as a reference.
2. At rest, more negative inside then outside
3. moves three Na+ out of a cell and two K+ into the cell.
How does a electrical signal start?
Starts with small changes in voltage across cell membrane of dendrites and cell body. Small changes start when a stimulus causes a gated ion channel to open.
As positive comes into a neuron, mv becomes positive
mv = -70 to -60
Conduction of Nerve Impulses
At start of axon, summation of small changes depolarizes the neighboring region of axon membrane.
gated channels voltage
A change in the membrane potential causing the movement of certain charged regions on a channel protein, altering its shape.
Example: voltage-gated Na+ channel in excitable tissues
gated channels chemical
a molecule that binds to a specific receptor on a gated ion channel, causing it to open or close, thus allowing ions to flow across the cell membrane in response to a chemical signal
Ion concentration gradients
favor diffusion of potassium ions out of cell and sodium ions into cell. Potassium ions diffuse through leak channels more easily than sodium ions.
What starts an electrical signal along axon
excitatory postsynaptic potentials from a presynaptic neuron
Ion movement during an electrical signal
specialized channels in the plasma membrane open and allow rapid ion movement into or out of the cell
Neurotransmitters
chemical messengers that cross the synaptic gaps between neurons
Pain
an unpleasant sensory and emotional experience associated with actual or potential tissue damage
Endorphins
naturally occurring proteins that the body releases in response to pain. "morphine within"--natural, opiatelike neurotransmitters linked to pain control and to pleasure.
Opiates
opium and its derivatives, such as morphine and heroin; they depress neural activity, temporarily lessening pain and anxiety. However, opioids are able to act more quickly than endorphins because they can move directly into cells
Serotonin
Affects mood, hunger, sleep and arousal. Undersupply linked to depression.
Depression
genetic, biological, environmental, and psychological factors play a role in depression. Depression is NOT a consequence of low secretion.
SSRI
selective serotonin reuptake inhibitor
SSRI function
block reuptake of serotonin (Prozac, Zolaft, etc.)
Different types of treatments for depression
Different SSRIS (Prozac, Zolaft, etc.)
CNS (central nervous system)
brain and spinal cord
Protection of CNS
scalp and skin, skull and vertebral column, meninges, cerebrospinal fluid, blood brain barrier
Blood brain barrier
Blood vessels (capillaries) that selectively let certain substances enter the brain tissue and keep other substances out
White Matter
Bundles of myelinated zoons, communication, connects gray matter areas to each other to other parts of body.
Gray Matter
(outside) Cell bodies, dendrites, unmyelinated axons, integrates information to produce a response. 40% of braine, 94% of oxygen.
PNS (peripheral nervous system)
the sensory and motor neurons that connect the CNS to the rest of the body
Hypothalamus
Regulates homeostasis and autonomic functions.
CNS (central nervous system)
brain and spinal cord
Cerebrum
Largest part of brain, Area of the brain responsible for all voluntary activities of the body
Parietal lobe
A region of the cerebral cortex whose functions include processing information about touch.
Occipital lobe
visual processing
Sensory area
the site in the brain of the tissue that corresponds to each of the senses, with the degree of sensitivity related to the amount of tissue
Motor Area
A region of the frontal lobe involved in regulating movement
Primary motor area
sends impulses to skeletal muscles, located in frontal lobe
Premotor Cortex
The region controlling learned motor skills.
Prefrontal cortex
part of frontal lobe responsible for thinking, planning, and language
Thalamus
the brain's sensory switchboard, located on top of the brainstem; it directs messages to the sensory receiving areas in the cortex and transmits replies to the cerebellum and medulla
Cerebellum
Brain region coordinating movement and balance.
Hippocampus
Involved in memory formation and spatial navigation.
Amygdala
Processes emotions and fear responses.
Brainstem Functions
Controls vital functions like breathing and heart rate.
Limbic System
Emotional and memory processing brain structures.
Reticular Activating Center
Regulates consciousness and alertness.
Somatic Nervous System
Controls voluntary muscle movements.
Sympathetic Nervous System
Prepares body for 'fight or flight' response.
Parasympathetic Nervous System
Promotes 'rest and digest' activities.
Dual-innervation
Organs receiving signals from both ANS divisions.
Sensory Reception
Detection of stimuli by sensory organs.
Perception
Interpretation of sensory information.
Adaptation
Decreased sensitivity to constant stimuli.
Transduction
Conversion of stimuli into neural signals.
Mechanoreceptors
Respond to mechanical pressure or distortion.
Chemoreceptors
Detect chemical stimuli like taste and smell.
Nociceptors
Pain receptors responding to harmful stimuli.
Olfactory Receptor Cells
Detect odor molecules for smell.
Taste Buds
Structures for detecting taste stimuli.
Neural Processing in Retina
Conversion of light into neural signals.
Aqueous Humor
Fluid maintaining eye shape and pressure.
Glaucoma
Condition caused by increased intraocular pressure.
Cornea
Transparent front part of the eye.
Sclera
White outer layer of the eyeball.
Myopia
Condition causing difficulty seeing distant objects.
Rods
Photoreceptors for low-light vision.
Cones
Photoreceptors for color vision.
Decussation
Crossing of nerve fibers in the brain.
Pinna
Outer ear structure capturing sound waves.
Tympanic Membrane
Eardrum vibrating in response to sound.