What do Neutrophils, macrophages, and dendritic cells do to unwanted substances by phagocytosis?
they engulf unwanted substances by phagocytosis
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2
Neutrophils undergo what after phagocytosis and become a component of pus?
undergo apoptosis after phagocytosis
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3
(Neutrophils) Dendritic cells destroy what?
destroy particles and present fragments to T-Lymphocytes
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4
(Neutrophils) Dendritic cells initiate what type of immunity?
initiate adaptive immunity
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5
(Neutrophils: Dendritic cells) Macrophages can preform what?
can perform antigen presentation
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6
Basophils and Mast cells promote what?
promote inflammation
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7
Basophils circulate in what?
circulate in the blood
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8
Mast cells reside in what?
reside in connective tissue, mucosa, and internal organs
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9
Mast cells release what?
Histamine
Heparin
Eicosanoids
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10
(Mast cells) Histamine increases what?
increases vasodilation and capillary permeability
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11
(Mast cells) Heparin is what?
is an anticoagulant
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12
(Mast cells) Eicosanoids increase movement from blood to what?
to injured tissue
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13
(Mast cells) Eicosanoids attract what?
attract immune cells (chemotactic chamicals)
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14
Natural Killer cells are created when?
created when we are born
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15
Natural Killer cells destroy unwanted cells through what?
through apoptosis
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16
natural Killer cells performs what?
performs immune surveillance
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17
(Natural Killer cells) What does immune surveillance do?
patrol the body detecting unhealthy cells
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18
Natural Killer cells detect what unhealthy cells?
virus-infected cells, bacteria-infected cells, tumor cells, and cells of transplanted tissue
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19
Natural Killer cells destroy unhealthy cells by what?
by cytotoxic chemicals
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20
(Natural Killer cells) What happens first when cytotoxic cells destroy unhealthy cells?
the natural killer cells release perforin which creates a transmembrane pore in the unwanted cell
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21
(Natural Killer cells) What happens second when cytotoxic cells destroy unhealthy cells?
granzymes enter the pore created by perforin and cause apoptosis
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22
Eosinophils do what to enzymes and other toxic substances to attack multicellular parasites?
they degranulate (release granules) enzymes and other toxic substances
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23
Cells of the innate immune system recognize microbes as foreign because of surface molecules called ________ and proteins that allow for self-recognition.
glycocalyx
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24
Immune cells have what type of recognition receptors on the cell surface that bind to patterns on other cells?
they have pattern recognition receptors
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25
When surface molecules on cells don’t match the normal body cells, the immune cells target the cells for what?
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