Autoimmune Hemolytic Anemias (AIHAs)
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5 Terms
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What are the 3 main types of Autoimmune Hemolytic Anemias (AIHAs)?
1. Cold Agglutinin Disease (CAD)
2. Paroxysmal Cold Hemoglobinuria (PCH)
3. Warm Autoimmune Hemolytic Anemia
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What is Cold Agglutinin Disease (CAD)?
IgM to human RBC I antigen
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What is Paroxysmal Cold Hemoglobinuria (PCH)?
IgG coats RBCs at cold temperature
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What is Warm Autoimmune Hemolytic Anemia?
IgG coats RBCS at 37 C and cells are lysed
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What is the main diagnostic test for Autoimmune Hemolytic Anemias (AIHAs)?
Direct antiglobulin test (DAT; Direct Coombs test)
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Flashcards (37)