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parts of depressive disorders, bipolar disorders, and psychotic disorders
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social perspective of depressive disorders: parental depression
passive gene environment correlation; heritability and genetic factors
parents themselves with depression will model depressive behaviors onto their children
social perspective of depressive disorders: major childhood stressors
traumatic event or other sources of stress—excessive cortisol desensitizes a person
social perspective of depressive disorders: interpersonal stressors
caused by friendships and relationships
grief, loss, rejection, humiliation, etc…
social perspective of depressive disorders: low social support
no support structure and lack of help from others
evocative environment correlation: depressive disorders
vulnerable individuals may increase their own stress through things like catastrophizing, withdrawal from social interaction, etc…
sociocultural factors of depressive disorders: prejudiced individuals and those in poverty
increased risks against individuals who are prejudiced or those in poverty due to learned helplessness and a lack of a sense of control
sociocultural factors of depressive disorders: gender differences
genetic and biological differences (e.g. hormones), stress of gendered prejudice, gender roles, interpersonal roles, cognitive emphasis on rumination, and higher rates of traumas and sexual maltreatment
bipolar I disorder
0.6% 12-month prevalence; 0.6% lifetime prevalence (signifies lifetime condition); usually onsets in adolescence or early adulthood; 1:1 gender ratio
at least one manic episode; commonly comorbid with depressive disorders—precedes manic episodes
symptoms in bipolar disorders
severe impairment in judgement and insight, but no inherent distress in periods of mania due to grandiosity; increase in risk of suicidality and impulsivity
suicidality in bipolar disorders
60x greater risk of suicide in those with bipolar disorders
for every 3 attempts, there is one death due to suicide
suicide completion is higher in bipolar II disorder because focus inhibition is greater in bipolar I disorder
specifiers for bipolar 1 disorder: anxious distress
bipolar 1 disorder comorbid with anxiety disorders
specifiers for bipolar 1 disorder: mixed features
comorbid with depressive disorders simultaneously; most dangerous due to suicidal ideation in depression and impulsivity in mania
specifiers for bipolar 1 disorder: rapid cycling
four or more episodes within a year
bipolar II disorder
at least one hypomania episode, no manic episodes, and at least two major depressive episodes
0.8% 12-month prevalence; once you have a bipolar disorder, the condition is permanent
10% of those with this condition go on to have bipolar I disorder
cyclothymic disorder
0.4% - 1% prevalence; 15-50% of those with this disorder go on to have one of the bipolar disorders; precursor to BPDs
at least one hypomanic episode, no manic episode, and mild depression where hypomania or depression is always present
biological causes of bipolar disorder: heritability
71% heritability; very commonly heritable disorder with risks increasing with closer relatives
biological causes of bipolar disorder: neurotransmitters
dysregulation of serotonin (high in mania, low in depression)
elevated glutamate activity (excitatory neurotransmitter)
biological causes of bipolar disorder: genetic association
bipolar disorders are more genetically associated with schizophrenia than unipolar disorders
biological causes of bipolar disorder: brain activity
excessive brain activity in the amygdala (emotion), striatum (movement, reinforcement, learning), and thalamus (possibly causes hallucinations)
psychological causes of bipolar disorder
high sensitivity to rewards (goal attainment), lack of insight, high value on creative output, which causes low compliance with treatment
bipolar disorders are purely genetic
biological treatment for bipolar disorders: lithium
most effective form of treatment for bipolar disorders in about 67% of cases; brings individuals out of mania, decreases suicide risk, and prevents future manic episodes
biological treatment for bipolar disorders: other medications
atypical antipsychotics (risperdal, abilify, geodon)
anticonvulsants/anti-seizure medication (lamictal, divalproex sodium, trileptal)
antidepressants and bipolar disorders
tricky when providing individuals during a depressive disorders because giving somebody with a bipolar disorder antidepressants can cause mixed-features specifier for bipolar disorders, increasing suicide risk
psychological treatment for bipolar disorders: CBT, Interpersonal, & social rhythms therapy
cannot treat bipolar disorders
therapies to help individuals get on a steady schedule to reduce future relapses of manic/depressive episodes
biological treatment for bipolar disorders: LEAP
cannot treat bipolar disorders
therapy for lack of insight and medication compliance
stands for Listen, Empathize, Agree, and Partner
biological treatment for bipolar disorders: behavior & supportive therapy
support medication compliance, and help patients adjust and cope with bipolar disorder diagnosis
suicide
intentionally kills oneself
died of/by suicide preferred over committed suicide
non-suicidal self-killing
euthanasia: voluntary ceasing of one’s life early due to terminal conditions and illnesses that would end life regardless
suicide attempt
self harm with some intent to die some lethal consequence
completed suicide is preferred over successful suicide
suicidal ideation
thoughts about suicide
non-suicidal self-injury
intentional physical self-harm with no intent to die
suicidality demographics: attempted suicide
females > males; adolescents and young adults
suicidality demographics: completed suicide
males > females; older adults older than 65 y.o.
frequency of suicide
34,000 americans die every year due to suicide; percentage may be higher 25-35% due to underreporting or misinterpreting deaths as non-suicide
2x as many firearm deaths are caused by suicide rather than homicide
suicide is the 3rd leading cause of death in adolescents in teens and young adults (increased risk as people grow older) than it is for the elderly
characteristics of suicide: marital status
widowed or divorced individuals are at higher risk of suicide
characteristics of suicide: occupation
certain occupations like law enforcement, doctors, and dentists are more likely to die by suicide due to access of means to kill oneself and desensitization
characteristics of suicide: socioeconomic status
loss in socioeconomic status (such as dropping in status)
characteristics of suicide: methods
50% of completed suicides are caused by firearms
70% attempts are caused by drugs
characteristics of suicide: religion
reported suicide rates are lower in catholic and islamic countries; may be due to underreporting or misinterpreting deaths due to suicide being taboo
characteristics of suicide: race & ethnicity
suicide rates higher in American Indians > White Americans > People of Color (based on access to community)
characteristics of suicide: historical/political
suicide rates lower in strife due to increase in community, and rates are higher during social or political change
characteristics of suicide: intent
never always ambivalent—10% of attempters die
causes of suicide: biological
suicidality risk factors are 30-55% heritable
low levels of serotonin is associated with depressed and non-depressed suicidal ideation and reduces access to adequate depression treatment
causes of suicide: antidepressants
those with mental illnesses often take anti-depressants to treat it
not all symptoms dissipate at the same rate when receiving treatment; natural remission may occur as well
antidepressants in depressive episodes of bipolar disorders can increase suicidality due to mix-features
causes of suicide: psychological
>90% of completed suicides have at least one of these disorders: depressive disorders, bipolar disorders, substance use disorders, and schizophrenia
depression: slight mood increases causes higher suicidality due to slightly improved motivation; hopelessness is the strongest predictor for suicide
tunnel vision and inability to consider alternatives to obvious solutions
alcohol reduces inhibition, and inhibition is key preventing self-harm
social causes of suicide: painful social emotions
loneliness, shame, rejection, grief, relationships, distress, etc.
social causes of suicide: joiner’s interpersonal-psychological theory
perceived burdensomeness to others, thwarted belongingness in communities and social circles, and overcome inhibitions/acquired means of suicide
social causes of suicide: interpersonal maltreatment
abuse, bullying, shunning, etc.
causes of suicide: copycat suicides
romanticization of suicides and detailed descriptions of methods of suicide
causes of suicide: “post-vention”
reduce grief of immediate members of an individuals who commit suicide to reduce risks of secondary traumatization and “copying” the suicide
causes of suicide: contagion
exposure to mental illness can cause individuals to mimic abnormal behaviors and mental illnesses, and lead them to believe they have mental illnesses
papageno effect
media depictions that reduces suicide risk
werner effect
media depictions that increases suicide risk
sociocultural perspective of suicide: access to firearms
easy access to firearms mean greater risks of completed suicides
67% of firearm deaths are caused by suicides, and 50% of suicides are caused by firearms
firearms are lethal, and non-firearm attempters are savable
sociocultural perspective of suicide: elderly
attitudes toward the elderly increases suicidality
higher in white american elderly, but lower in japanese elderly
sociocultural perspective of suicide: immigrants
first-generation immigrants are at greater risk of suicidality due to lower social connectedness with the culture and surrounding community
sociocultural perspective of suicide: LGBT
risk of interpersonal stress and lack of connectedness to the predominately straight community
sociocultural perspective of suicide: cultural beliefs
beliefs about death and dying (e.g., cultural stigma)
suicide prevention: tertiary prevention
“post-vention” to help those affected by an individual who completed suicide like immediate family members and friends
preventative measures such as counseling to prevent copycat suicides and reduce risk of further traumatization
suicide prevention: secondary prevention
early detection, prevention, and treating individuals who have mental illnesses, are at risk of suicidal ideation, or following significant stressors/crises
suicide prevention: primary prevention
preventative measures to stop suicidal ideation before they occur, general community initiatives to reduce stigmas and education about suicide, and preventative means to stop suicide access (e.g., firearms)
psychotic and related disorders: delusions
fixed false beliefs that can be influenced by culture and be described as bizarre/non-bizarre
these beliefs are often “immune to logic” and cannot be disputed
types of delusions: persecutory
false beliefs that one is being persecuted against (e.g., being watched by the government, being stalked by assassins, etc.)
types of delusions: referential
false belief that neutral environmental factors, events, objects, and behaviors of others are of significance to oneself (e.g., interpreting other people talking as them speaking secret messages to you)
types of delusions: grandiose
false beliefs consisting of overtly confident ideas like extreme riches or supremacy over others (e.g., believing oneself to be wealthy)
types of delusions: erotomaniac
false belief that someone of note is in love with oneself
types of delusions: nihilistic
false belief that oneself, the world, or others are dead, do not exist, or are decaying
types of delusions: somatic
false beliefs that one’s internal or external bodily functions are abnormal
types of delusions: thought withdrawal/insertion
false beliefs that one’s thoughts are not their own and are given to them in their brain or being stolen from them by an entity
types of delusions: control
false beliefs where one believes someone is taking control of their actions, thoughts, and autonomy
psychotic and related disorders: hallucinations
experiencing sensory stimulation despite a lack thereof (no stimuli; they do not exist)
non-psychotic individuals can hallucinate through drug use
five senses: hearing, sight, touch, taste, and smell
psychotic and related disorders: disorganized speech
not correlated with disorganized thought
loose associations of different topics in a string of words
clang associations (words that rhyme), word salad (incoherent words), and abstract language (usually nonsensical)
psychotic and related disorders: disorganized behavior
acting in ways that is grossly and actively bizarre or illogical, typically never achieving anything and contradictory
e.g., barefoot in the snow, clapping and cheering at nothing, and excessive mail “sorting” that doesn’t really sort it
hypocatatonia
speech and movement drastically decreased; waxy flexibility
hypercatatonia
movement drastically increased with no clear goal
e.g., pacing, waving arms frantically, jumping up and down excessively
psychotic and related disorders: negative symptoms
removal of existing functions; alternatively, a lack of normal, pre-existing functions
“subtract, remove, negative”
often very impairing more than positive symptoms
negative symptoms: diminished emotional expression
constricted, blunted, or flattened expression of emotions in social scenarios that warrant them
e.g., not feeling sad at a funeral of a loved one
negative symptoms: avolition
little or no motivation
negative symptoms: alogia
little or no speech
negative symptoms: anhedonia
little or no ability to enjoy pleasurable activities
negative symptoms: asociality
little or no desire for social contact
psychotic disorders: cognitive impairment
not exclusive to psychotic disorders but very common in it
deficits in executive functioning (planning and higher functions), learning and memory, working memory and attention, logic and abstract thinking, verbal skills, and general intelligence
sharp cognitive decline after the first psychotic episode
brief psychotic disorder
1 day to 1 month; any longer would upgrade the diagnosis
brief symptoms of psychosis that goes into remission shortly afterward with no significant cognitive impairment
caused by major stressors
schizophreniform disorder
1 - 6 months; any longer would upgrade the diagnosis; usually more prevalent in women
67% of individuals go on to have schizophrenia
schizophrenia
6 months or more; M > F (differs in onset only); 0.7% prevalence
5-6% die by suicide due to the impairing and distressing nature of the disorder; 20% attempt
schizoaffective disorder
0.3% prevalence; generally M = F
combination of schizophrenia and bipolar I disorder (mania/depression); the “in-between” of the two disorders
delusional disorder
<0.1% prevalence; F = M; difficulty in diagnoses and people getting diagnosed due to lack of severity
consists of ONLY delusions and delusions that are non-bizarre; most people go on to live normal lives depending on severity and type of delusions
anosognosia
belief that oneself is not ill (physiologically and/or psychologically); a person is not in denial but rather believes logically they are healthy despite obvious symptoms
present in half of all schizophrenic, schizoaffective, and bipolar I disorders
effects of anosognosia
effects are permanent and caused by neurological factors that must be worked around with by caretakers
not responsive to evidence proving illness and correlated with cognitive impairment
denial
emotional, temporary response to learning of diagnoses that is correlated with emotional distress or poor personality function
can be treated with talk therapy
course of schizophrenia & related disorders
prodome → 1st psychotic episode → 1 of 3 scenarios:
severe and chronic disability caused by schizophrenia
few or residual symptoms in between episodes; function still limited
permanent residual symptoms and periodic relapses; function supported independently
prodrome
precursor symptoms to psychotic episodes/disorders; negative symptoms first, then positive symptoms
the mentally ill, violence, and crime
the mentally ill are more susceptible to crimes than being the perpetrator of crimes
crimes committed by the mentally ill are usually non-violent, and even if they were, they are usually committed against known persons; insanity plea is rare and most go on to suffer
precursors to committing violent crimes include previous tendency of violence and psychopathy, untreated individuals, comorbid substance abuse, and the male gender
biological factors for schizophrenia: heritability
80% heritability; likelihood increases if relatives have schizophrenia
biological factors for schizophrenia: brain abnormalities
loss of white and grey matter (brain matter) especially in frontal lobes and enlarged ventricles
biological factors for schizophrenia: brain chemistry abnormalities
dysregulated dopamine activity; dopaminergic pathways are affected
biological factors for schizophrenia: early developmental delays
children have higher rates and signs of neurological “soft signs;” signs and symptoms that show increased risk for schizophrenia
e.g., missing claps excessively during childhood
dopaminergic pathways: mesolimbic
dopamine increases result in positive symptoms
dopaminergic pathways: mesocortical
dopamine increases result in negative symptoms
dopaminergic pathways: nigrostriatal
dopamine increases result in movement issues