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mRNA is read is 3 letter sequences called
codons
What type of mutation has occurred? If AGCUCG changes to AGCAUCG
Frameshift (Insertion)
When this specific type of substitution mutation occurs it does not end up changing the amino acid sequence produced
Silent mutation
Why is DNA replication considered semi conservative
each new DNA molecule has one strand from the original molecule, and one new strand
If the parent DNA strand is 5' ATCGATACTAC 3', what will the daughter strand be after DNA replication?
(include the direction the strand is running in, think about if it starts with 5’ or 3’)
3’ TAGCTATGATG 5’
Starting with a parent strand of DNA, what two processes need to occur first before translation can occur
Dna replication and transcription
Uracil (U) is present in what type of molecule
RNA
Translate the following: AUG GAC CUA
Met asp leu
A reading frame shift can be caused by what types of mutations
Insertion or deletion

This substitution results in what type of mutation
Missense
How could you mutate this sequence of RNA to result in a nonsense mutation: AUG CAA UAG
Change C to U

What process is occurring
Transcription
This strand of DNA goes through Transcription: ATG GCA CCC
What will be the resulting strand of mRNA produced
UAC CGU GGG
Translation results in the formation of
Amino acids or proteins

This is a molecule of
RNA
What will be the resulting mRNA from this DNA sequence: GAT-TAC-AGA
CUA AUG UCU
Transcribe the following: CGA GGC AAC
GCU CCG UUG
Translate the following: GCA CCG AAG
Ala pro lys
What type of mutation will have the most minimal impact on an organism and the proteins produced
silent
Why is a substitution not considered a reading frame shift mutation
It does not impact the rest of the codons that are read after the mutation
This is the original strand of RNA: AUG AAA UGA
Create a mutated strand that results in a missense mutation