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What are emergent properties?
bringing together simple units to make a more complex unit
What are the three parts of cell theory?
All organisms are made up of cells
The cell is the fundamental unit of life
Cells came from preexisting cells
What is life? (biologically...)
ability to reproduce, respond to the environment, harness energy from the environment and evolve over time
What are the three universal properties of cells?
maintaining homeostasis, store and transmit information, and transfer energy
What are the functions of the cell membrane?
acquiring and exchanging ions and the building blocks of macromolecules
releases waste products into the environment
What is homeostasis?
the active maintenance of stable internal conditions of a cell
Why is homeostasis necessary in cells?
it is important for maintain chemical reactions, protein folding, and other cellular functions
Why is homeostasis an "active process"?
it requires continual interplay between the inside and outside of the cell
What are proteins?
key structural and functional molecules that do the work of the cell
How do cells reproduce?
DNA guides the synthesis of RNA which is then used to direct protein synthesis (Central Dogma)
Why are cells dependent on proteins?
they determine internal structure, shape, ability to move, and various chemical reactions
What are ribosomes?
complex structure that is a site where the protein is assembled (translation)
What is metabolism?
chemical reaction by which cells transfer energy from one form to another and build and break down molecules
What is ATP?
stored energy made from chemical reactions that enable growth, division, and moving substances into and out of the cell
What is catabolism?
set of chemical reactions that break down molecules into smaller units (release ATP/heat)
What is anabolism?
set of chemical reactions that build molecules from smaller units and require an input of energy (ATP)
(synthesizes carbohydrates and proteins)
How does protein structure determine its function?
the order of amino acids (R-groups) determine the folding
How does DNA structure aid in its function?
the double helix can divide due to weak hydrogen bonds and can then be replicated
What is the nucelus?
house of genetic information
What is cytoplasm?
space between organelles in a cell
What are prokaryotes?
cells without a nucleus and membrane-bound organelles
What are the two domains of prokaryotes?
Bacteria and Archaea
What are the properties of prokaryotes?
no nucleus
have flagella
plasmids
asexual
DNA in nucleoid
cell wall = peptidoglycan
more chemically complex
How is DNA organized in prokaryotes?
located in the nucleoid in strands in many loops
OR
in plasmids (circular molecules of DNA)
How are the domains of prokaryotes different?
structure of the cell wall, how DNA synthesizes RNA and relationships to eukaryotes
What are eukaryotes?
cells with a nucleus
What is a eukarya?
domain consisting of all organisms that have a nucleus; includes protists, plants, fungi, and animals
How does DNA travel to replicate?
directs synthesis in the nucleus then RNA synthesizes protein in the cytoplasm
How is DNA replication different in prokaryotes and eukaryotes?
Prokaryotes: Single process
Eukaryotes: Multiple regulated processes
What are organelles?
membranes that divide the cell contents into smaller spaces specialized for different functions
What are the key properties of eukaryotes?
nucleus
many linear chromosome
complex regulation of DNA and RNA
Ribosomes
Cilia
What is the cytosol?
jelly-like material outside of the nucleus and organelles
What are the major differences between the eukaryotes and prokaryotes?
RNA/protein synthesis, ribosome size, lipids that make up membranes, and flagella vs. cilia
What are cilia?
rodlike structures that extend from the surface of the cell
What are nonmotile cilia?
cilia that don't move and serve as a sensory function
What are motile cilia?
cilia that move and propel the movement of cells or fluid
What is surface area?
the total amount of area of the outer surface of an object
What is the cytoskeleton?
protein fibers to maintain shape and assist in movement
Why is the surface area to volume ratio important?
-If the ratio is too small then substances will not enter the cell as quickly
- If the ratio is too small then cells may overheat because the metabolism produces heat faster than it is lost
What are vesicles?
small membrane-enclosed sacs that transport substances within a cell or from the interior to the exterior of the cell
What is the function of vesicles?
take pieces of membrane or internal contents of the organelle then fuse with the membrane to re-fuse or unload their contents
What is the endomembrane system?
the interconnected membranes of the cell (chemical communication system)
What is the function of the endomembrane system?
Allows for the cell to compartmentalize different areas to serve different functions (diversity of enzymes)
What is the endoplasmic reticulum?
an organelle involved in the production of proteins and lipids
single membrane
Why does the ER need increased surface area? (maze-structure)
to allow for larger protein production via ribosomes
What is the difference between free ribosomes and membrane bound ribosomes?
Free ribosomes send proteins directly to the cytoplasm (not other organelles or membrane)
What are enzymes and where are they made?
proteins (rough ER) that accelerate the rate of a chemical reaction
What is the function of the smooth ER?
site of fatty acid and phospholipid synthesis
Why do cells have organelles?
increase surface area
cell specialization (aid in function)
protection
resource managers (chemical concentration variations)
What is the nuclear envelope?
double membrane that surrounds the nucleus
What are nuclear pores?
holes in the nuclear envelope where things can pass into and out of the nucleus
What is the function of the golgi apparatus?
sorts and modifies proteins and lipids from the ER
acts as a sorting satiation
where carbohydrates are added to proteins/lipids
single membrane
What are cisternae?
flattened membranous sacs in the golgi apparatus
How do molecules move through the endomembrane system?
vesicles
Why do proteins move backward from the golgi?
if there was an error in production or to recycle components
What are lysosomes?
specialized vesicles derived from the golgi that degrade damaged or unneeded macromolecules
What is the mitochondria?
organelles that harness energy from organic molecules (mostly carbohydrates)
What is chemical respiration?
a series of chemical reactions in which organic molecules are broken down and the energy stored in organic molecules is converted to ATP
Describe the membrane structure of a mitochondria.
an outer membrane and a highly convoluted inner membrane whose folds project into the interior
What is the mitochondrial matrix?
space enclosed by the inner membrane
Where does cellular respiration occur?
cytosol, mitochondrial matrix and inner mitochondrial membrane
What is the chloroplast?
organelle that captures energy of sunlight to synthesize simple sugars (plants/algae only)
double membrane
What is photosynthesis?
process of capturing sunlight to synthesize simple sugars (Co2 in, O2 out)
What is a thylakoid?
The organelle in which light dependent reactions take place.
What is a grana?
the stacks of thylakoids embedded in the stroma of a chloroplast.
What is chlorophyll?
light collecting molecule (pigment)
serves key role in ability to capture energy
What are microfilaments?
extensively branch beneath the cell membrane and reinforce the cell membrane and organize proteins a associated with it
What are microtubes?
hollow tubelike structures that help maintain cell shape and internal structure
What are the functions of microtubes?
help the cell withstand compression and guide the arrangement of organelles in the cell
What is the function of the cell wall?
provide structural support and protection of the cell because it is rigid and resists expansion
What is the cell wall composed of?
carbohydrates, proteins, polysaccharide, cellulose***
What is turgor pressure?
the force exerted by water pressing against an object
(provides structural support in plants)
What is the function of the vacuole?
absorb water and contribute to turgor pressure
store water, nutrients, ions, and waste
Why do cells expand?
water pressure and chemical concentration variation
What is volume?
total amount of space an object occupies
Why do some cells want a larger surface area?
more movement of stuff into and out of the cell
Which increases faster: volume or surface area? Why is this helpful?
Volume, used to determine growth of organisms
What is isometry?
same measure/shape but an increase/decrease of size
What is allometry?
different measure/shape with a change of size
What is diffusion?
net movement of molecules from regions with higher concentrations to regions of low concentration
What are the pros and cons of diffusion?
Cons: takes a long time
Pros: disposes waste and energy
What is bulk flow?
the movement of a fluid driven by pressure differences
(used to transport nutrients to places far away from source)
What is the function of the cell membrane?
separates cells from their external environment and defines compartments within eukaryotic cells that allow them to carry diverse functions
What does amphipathic mean?
having both hydrophilic and hydrophobic regions
Describe the structure of phospholipids.
phosphate head (polar, hydrophilic)
fatty acid tails (nonpolar, hydrophobic)
What makes up a micelle membrane?
lipids with bulky heads + single fatty acid tail
What makes up a rectangular membrane?
lipids with smaller heads and double fatty acid tails
What is the lipid bilayer?
two layers of lipids in which the hydrophilic head group are on the outside (intact with water) and the hydrophobic tails are sandwiched inbetween
What are liposomes?
spherical structures with an inner and outer space (resembles a cell)
What does "dynamic membrane" mean?
fluid with lateral movement of lipids and other components to allow for versatility
Why is the cell membrane "dynamic"?
weak van der Waals forces break and travel quickly with flexibility
How do we determine membrane fluidity?
Long fatty acid chains = less fluid
# if carbon-carbon bonds in tails (saturated is less fluid)
How does cholesterol impact membrane fluidity?
High temperature makes it more fluid and lower temperature makes it less fluid
What is the function of cholesterol in the cell membrane?
helps maintain a consistent state of membrane fluidity by preventing dramatic transitions in fluidity as temperature changes
What are lipid rafts?
lipids assembled in a defined patch (anchor points) in the cell membrane
What are transport proteins?
proteins which move ions or other molecules across the membrane
What are receptor proteins?
proteins that allow the cell to receive signals from the environment
What are some functions of proteins in the cell membrane?
transport
receptor
speed up chemical reactions
serve as anchors
maintain structure and shape
What are integral proteins?
proteins permanently associated with the membrane
What are transmembrane proteins?
proteins that extend for the entire membrane