immunity drug adverse effects

cyclosporine

nephro/hepatotoxicity, infections, hirsutism, and gingival hyperplasia

tacrolimus

nephro/neurotoxicity

cytotoxic immunosuppressants

bone marrow suppression, infertility, and hair loss

1 gen H1 antagonists/antihistamines

sedation, CNS effects, anticholinergic effects, respiratory depression, and local tissue injury

COX 1 inhibitors

GI ulcers, bleeding, and nephrotoxicity

COX 2 inhibitors

nephrotoxicity and MI/stroke

aspirin

bleeding, nephrotoxicity, salicylism, reye syndrome, and pregnancy complications

celecoxib

GI ulcers, nephrotoxicity, HTN, and edema

early acetaminophen OD

N/V/D, sweating, and abdominal pain

glucocorticoid withdrawal

hypotension, hypoglycemia, myalgia, arthralgia, and fatigue

glucocorticoids long-term

adrenal insufficiency, osteoporosis, infection, myopathy, hyperglycemia, F & E imbalance, child growth delay, psych disturbances, cataracts/glaucoma, PUD, and cushing’s

salicylism

tinnitus/vertigo, sweating, HA, and dizziness