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Epi and Cocaine
EPI is contraindicated
Oral mucosa irritation
result of drug administration, not the drug itself
Adrenergic drugs should not be used when?
Patients with angina, uncontrolled hypertension, and uncontrolled hyperthyroidism
Atropine
used pre operatively to decrease salivary flow for dental procedures
Aspirin in children
Reye's syndrome
Pilocarpine
(Salagen)- treat xerostomia - (pillow// slobber on pillow)
Evoxac
"evacuate the slobber" ; treats xerostomia
NSAIDs and phenytoin
can increase phenytoin (seizure) levels
Acetaminophen contraindicated for
current and past alcoholics
Acetaminophen drug of choice for who?
patients on anticoagulants or with peptic ulcers
Ibuprofen can decrease the effects of:
ACE inhibitors
Beta Blockers
Loop diuretics
Corticosteroids
Cyclosporine
Lithium
Most common opioid in dentistry
codeine (Tylenol 3)
Sign of overdose/addiction to opioid
pinpoint pupils
Opioids lead to
constipation
What are opioids not used for
chronic pain
Antibiotics used to kill
bacteria NOT viruses
most likely antibiotic to cause allergic reaction and anaphylaxis
Penicillin
Which penicillin is preferred
VK over G because pen G is inactivated by gastric acids
Penicillin is not effective against
penicillinase (breaks down penicillin) producing bacteria.
Augmentin
IS effective against penicillinase producing bacteria- it prevents penicillinase from breaking down amoxicillin.
amoxicillin and clavulanic acid
erythromycins most common side effect
GI upset
Premed with penicillin allergy
Azithromycin and Clarithromycin
Tetracycline used for
used to treat NUP/NUG and aggressive perio due to their excretion into the gingival crevicular fluid where they have an anti-collagenase effect
What is not allowed while taking tetracycline?
Milk- causes photosensitivity
All tetracyclines do what?
cross the placental barrier and are excreted in breast milk (stain babies teeth)
Clindamycin can lead to
pseudomembranous colitis (C-diff: Clostridium difficile)
Severe persistent diarrhea
If alcohol is ingested with Nitroimidazoles
it will make you very sick- similar to disulfiram (antabuse) with alcoholic - avoid Listerine (high alcohol content)
If a pt indicates they are taking rifampin or isoniazid only
they are likely taking it as a preventive agent
Nystatin
is used topically to treat candidiasis (thrush)
Diflucan
(Fluconazole) used to treat systemic fungal infections.
Local anesthetic agents inhibit
the influx of sodium ions
Function loss in this order with ANS:
Autonomic - temperature- pain- touch/pressure- vibration and motor // REGAIN in the reverse order
Esters are metabolized in the
plasma (BLOOD)
Esters have a high potential for what?
allergic reactions
Benzocaine is an amide or ester?
is an ester and available as a topical
Amides are metabolized
in the liver
Prilocaine (Citanest) is associated with
methemoglobinemia (anemia that turns you blue)
Duration of action of anesthetics (shortest to longest)
Mepivacaine (shortest)
Lidocaine
Prilocaine
Articaine
Bupivacaine (longest)
pKa (dissociation constant)
related to ONSET of action
Lower pKa = better absorbed
Protein binding capacity
related to DURATION of action
Stronger binding= longer duration
Lipid solubility
related to POTENCY More lipid soluble = more potent
Vasodilating properties
affect POTENCY and DURATION of action Less vasodilation (vasoconstrictor added) = more potent and longer duration
Vasoconstrictors are added to anesthetics for:
Decreased systemic absorption
Decreased absorption
Increased duration of action
Decreased bleeding
Max recommended dose of epinephrine is based on the pts health status
HEALTHY: 0.2mg epi per dental appt
ASA I or II
"Cardiac dose": 0.04mg epi per dental appt ASA III or IV Pregnancy, diabetes hypertension, etc.
Anesthetics WITHOUT a vasoconstrictor (plain solution)
Lidocaine: not available in dentistry in the US
Mepivacaine
Prilocaine
Local anesthetic pH
weak base and works poorly where there is infection due to the very acidic environment - increased dose may be needed in this area
Best way to reduce systemic toxicity from local anesthetic is:
Aspiration and inject slowly
Benzodiazepines and Barbiturates:
have no analgesic effect
Nitrous and oxygen tank colors
Nitrous: blue Oxygen: green
Nitrous oxide is excreted
exhalation
No biotransformation - inhaled and exhaled in same form
Preventing diffusion hypoxia
Place pt on 100% oxygen for 5 minutes following sedation
Diffusion hypoxia
rapid outward flow of C02 - decreasing ventilation - causing headache
Nitrous oxide / oxygen sedation maintains pt in what stage of anesthesia
Stage 1 anesthesia
Nitrous oxide / oxygen sedation can reduce the orofacial muscle tone in
cerebral palsy pts during dental treatment
Nitrous oxide abuse can lead to:
Neurologic symptoms similar to parkinson's disease and dementia
Numbness and tingling in the extremities
Supragingival nutrient source is
Saliva
Subgingival nutrient source is
GCF
class 3 and 4 furcations
Class IV furcation is the same as Class III, except the entrance to the furca is clinically visible because of advanced gingival recession
When can you start using fluoride mouthrinses for children
No fluoride mouthrinses under 6 yo
Where do you get cholesterol
Only animal products contain cholesterol not found in egg whites or plant foods- found highest in egg yolks, liver, organ meats
During tooth development, phosphorous deficiency results in:
Incomplete calcification of teeth
Failure of Dentin formation
Increased susceptibility to caries
What may well be recognized as the most important essential trace mineral for humans
Zinc
Amenorrhea:
missing at least 3 menstrual periods in a row
Lanugo:
Soft downy hairs all over body from anorexia
Phenylketonuria:
inability to metabolize amino acid phenylalanine- NO aspartame (Equal/Nutrasweet)
Marasmus:
waste away due to starvation; impairs brain development; in impoverished nations
Kwashiorkor:
when young children consume adequate calories and inadequate high-quality protein
Tertiary prevention
includes implants
Optimal fluoride level in drinking water
.7 ppm
Learning ladder
1:Unawareness
2: Awareness
3: Self-Interest
4: Involvement
5: Action
6: Habit
The goal for your program
is set FIRST ... then you develop measurable objectives
Summative evaluation:
evaluation of program AFTER implementation
Formative evaluation:
internal evaluation of program DURING planning
Eastman Interdental Bleeding Index:
Reversible
Uses wooden interdental cleaner
Assess papillary bleeding and indicates inflammation
DMFT/DMFS:
Decayed, missing, filled teeth/decayed, missing filled surfaces. --Irreversible
-Measures past and present caries experience in populations with adult dentitions
deft
primary teeth
Prevalence rate:
total number of cases at a given time
EXISTING
Null hypothesis:
NEGATIVE outcome; example: "There is no statistically significant differences between..."
Research hypothesis:
POSITIVE outcome; "There is a statistically significant difference between
Sample:
representative subset of the population
Random sampling:
best type of sampling; less bias
Convenience sampling:
creates bias; group is already together and convenient
Retrospective research:
investigates possible causes of disease; uses medical records
Experimental research:
investigates cause and effect and involves manipulation of variables
IRB (Institutional Review Board):
Reviews ethical implications of research study
Ensures safety
Standard Deviation
Square root of the variance
Most common and useful measure of dispersion
Correlation Coefficient Value (r-value)
Shows the strength of a relationship between two variables
Ranges from -1 to +1
Closer r is to 1: stronger the relationship
Closer r is to 0: weaker the relationship
Positive correlation
Direct relationship
r= +1: shows a perfect positive relationship
Negative correlation
Inverse relationship
INTRA-examiner Reliability
Consistent performance by the same investigator when using a data collection instrument
Example: your probing depths being consistent each time you collect data
INTER-examiner Reliability
Consistent performance by different investigators when using the same data collection instrument
Example: probe depths being consistent amongst a group of examiners
Endemic
Low but constant presence of disease in geographic region
Epidemic
Occurence of disease in excess of normal
Suddenly and spreading rapidly
Pandemic
An epidemic in which the disease may cross international borders to effect several countries
For Geriatric Pt:
Raise head of chair slowly and allow pt to sit for a few minutes before allowing to raise - avoid falling from hypotension
Deaf:
Do not shout
Remove mask when speaking
Pregnant:
2nd trimester is the safest
Daily fluoride rinses NOT systemic supplements
Client positioning may cause pressure on mothers vena cava creating hypotension: turn to LEFT side; pillow under right him
Tobacco Counseling to include
ASK: Do you smoke?
ADVISE: Importance of quitting
ASSESS: Level of readiness to quit
ASSIST: Let me know when you are ready
ARRANGE: set quit date
Medications used to help quit smoking
may have drug interaction with epinephrine
#1 cause of pancreatitis
Alcoholism