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What is the pathophysiology of vitilligo?
Autoimmune destruction of Melanocytes
What is the top treatment for vitiligo in order
1)Sunscreen 2) topical corticosteroids 3) Tacrolimus (TCIs)
What illness has White depigmented, macules , around offices and acral joints
Vitiligo
What are the three main causes for Melasma
Hormonal( pregnancy, OCP) UV Sunlight, Genetics
What skin condition, causes light/dark brown patchy, maculate hyper pigmentation along the forehead, upper lip
Melasma
What is the treatment of Melasma
1) Sunscreen, 2) Triple Blend (Hydroquinone, Trentinoin, Hydrocortisone
What skin condition appears around 30y/o is benign, clump of blood vessels on the surface of the skin. (Erythematous Papule)
Cherry Angioma
What is the treatment for Cherry Angioma
Treatment unnecessary, cauterize, cryosurgery
What skin condition presents with benign fibrous tumors
Fibroma
What is the treatment of a Fibroma
Shave/scissor biopsy, removal, excision
What skin condition presents with Benign tumor, neoplasm and fat cells
Lipoma
What is the treatment of Lipomas
Nothing, 2) surgical removal
What is the skin condition of macrophages containing fat droplets.
Xanthoma
What is the treatment is used for Xanthoma
Chemical, laser and surgical treatment. Treat underlying cause
What should be order with the presence of Xanthoma
Cholesterol Panel.
What skin condition presents in primarily adults over 50 with soft, orange, yellow plaque around eyelids
Xanthlasma
What is the treatment for Xanthlasma
Chemical, Laser, and surgical Treatment
What skin condition appears in 30y/o. Often presents as a stuck on waxy, warty, puritic and evolves.
Sebborhic Keratosis
What is the treatment of Sebborhic Keratosis
1) No Treatment, Cryotherapy, Shave, biopsy
What skin condition is button like, with deep papule and positive dimple signs, that forms from ingrown hair, or begging scar tissue
Dermatofibroma
What is the treatment for dermatofibroma
Punch Biopsy
What skin condition is present in newborn with light brown, macula/patch that are well circumscribed
Cafe au latte macule
When should you give a referral of a newborn with cafe au latte.
When they have >6 spots, or 5mm. Evaluate for neurofibromatosis
What skin condition presents as a vascular tumor in infants. That presents as a patch and becomes a red ulcerating plaque weeks later.
Infantile "strawberry" Hemangioma
What is the treatment of Strawberry Hemangioma
1) Resolves itself after 6-12mo, 2) Topical Timolol, 3) Systemic Propanalol
What is the skin condition that present with Non-blanching, non-evolving, that darkens with age
Port-wine Stain
What is the treatment of port-o wine stains
Pulse dyed laser
What is the skin condition, present in newborns described as a "stork bite or angel kiss.
Nevis Simplex, Salmon Patch
What is the treatment of Salmon Patch
1) Nothing, will fade over time
What is the skin condition that is a clump of melanocytes less than 1 cm. (Often benign)
Benign Nevi
What are the two ways Benign Nevi's formed
Hereditary (birthmark), Sun exposure
What is the Screen & treatment for Benign Nevi
Screening: ABCDE's, Surgical Removal if fails test, pt at risk
What skin condition presents as Rough,Scaly, itchy, pink in color that is caused by long term exposure in the sun.
Actinic Keratosis (AK)
what is actinic keratosis a precursor to?
squamous cell carcinoma (SCC)
Who are the demographic/ occupation most affected by Actinic Keratosis
(sun exposed) workers, over 40, Albino, light eyes
What is the treatment of Actinic Keratosis
(1,Cryotherapy, Electrodessication,)
(2 Topical Fluorouracil cream, Imiqmod)
What is the duration of Topical Fluorouracil when used on the Face.
2 weeks
What is the duration of Topical Fluorouracil when used on the body
4 weeks
What is the skin condition that presents with Pearly, Rolled edges.
Nodular BCC
What is the most common Basal cell carcinoma
Nodular
What skin condition presents with, pink, scales, plaques ( on trunk and limbs). Invades adjacent tissue
Superficial BCC
What skin condition presents with Nodular or superficial, HOWEVER have central black brown specks and globules. (Invades adjacent tissuesO
Pigmented BCC
What skin condition presents with skin colored scar/plaques, usually pink or white, invades adjacent tissue.
Sclerosis BCC /Morpheaform BCC
What skin condition presents with pink, pudunclated dome, papule shaped and often seen in back/lumboscaral/ Invades adjacent Tissue
Fibroepithelioma BCC/ Pinkus BCC
Who are the demographic/ occupation most affected by Basal Cell Carcinoma (BCC)
1) Men
2) fair skin people
3) immunosuppressed,
4) Genetic History/ Genetic Syndrome
What is the preferred Biopsy method for most BCC
1) Shave Biopsy
2)Punch biopsy for (morpheafrom)
What is the treatment for BCC
1) Surgical Excision
2) Mohs surgery
3) radiation
What skin condition presents with, non healing wound in a sun exposed areas often red, elevated with thick scaley margins, eroded lesion
Squamous Cell Carcinoma
What is the Precourser of SCC
Actinic Keratosis
What are the causes for Squamous Cell Carcinoma
1)Chronic Inflammation
2) Industrial Carcinogens
3) Inorganic arsenic
4)HPV
5)immunosuppression
What is the treatment of SCC
Excision biopsy, (4mm margins)
2) Mohs surgery
3) Radation
Repeat Check ups
What is the skin condition, presents as a metastasized Nevi, abnormal growth, asymmetrical, no clear defined border.
Melanoma
Who is at risk for Melnoma
1) Men
2) people with 5 atypical moles
3)People with Red hair/freckles
4)People with Sunburn before age 14
5) Family history, extensive tanning bed use
What is the treatment for Melanoma
1) Wide excision w/ clear margins (1-2cm)
2) If over 1mm- Lymph node Resection
3)Interferon therapy
4) Monoclonal AB (ipilummab)
What is the skin condition, that presents with clogged pores, increased sebum, and inflammation around the face, neck and trunk.
Acne Vulgaris
What age range are you unlikely to see acne.
Mid-childhood acne 1-7 years old. (Indicative of pituitary issue)
What is the treatment for mild acne
Benzoyl Peroxide (BPO), Topical Retinoid,
What is the treatment for Moderate Acne
Benzoyl Peroxide (BPO), Topical Retinoid, Topical Antibiotic
What is the treatment for severe acne
1) Isotertinoin ( BY ITSELF)
2) Benzoyl Peroxide, Topical antibiotic, Oral Antibiotic, Topical Retinoid, Glucocorticoids
What is the treatment for Hormonal Acne
1) spironolactone
2) oral contraceptives
3) Winlev
How long can you use Oral Teracyclines in treatment of acne before switching to BACTRIM
3 months
What skin condition presents with, facial flushing, redness, telangiectasia in lips nose cheeks and fingers
Rosacea
What are the treatment plans for Rosacea
T.A.M.S
1) Tetrocyclines (oral)
2) Azelic Acid
3)Metronidazole (topical)
4)Sodium Sulfacetamide (topical)
5) Antibiotics(topical)
Who are the demographic/ occupation most affected by Rosacea
1)Female
2) 30-50 years
3) Fair Skin
4)Genetic
5)Alcoholism (skin flushing)
What skin condition presents with papule/pustules causing inflammation of hair caused by bacteria/fungus
Folliculitis
What is the name of the BACTERIA responsible for Folliculitis
Staphylococcus Aureus
What is the name of the FUNGAL responsible for Folliculitis
Pityrosporum Folliculitis
What is the treatment for Folliculitis
Bacterial :Benzoyl Peroxide (BPO) / Antibacterial soap/ Clindamycin (anti-biotic lotion)
Fungal: Ketoconazole Cream
What is the skin condition, that doesn't respond to typical treatment. Appears after staying in a hot tub
Hot Tub Folliculitis
What is the name of the bacteria that causes Hot tub Folliculitis
Pseudomonas Aeruginosa
What is the treatment of Hot tub Folliculitis
1) BPO+ Topical Clindamycin
2) Oral antibiotics (Cipro)
What is the skin condition that, forms Folliculitis after shaving
Pseudo Folliculitis Barbe
What is the treatment of Pseudofolliculits barbe
1) Stop shaving
2) Lubcration during shaving/ single blade razor
3) BPO+ Clindamycin+retinol+moisturizer
What is the skin condition that presents with, interconnecting abscesses, atrophic scarring, with active papule and pustules
Acne Conglobata
What is the treatment for Acne Conglobata
Topical Antibiotics, oral Antibiotics, oral isotrentanoin and oral prednisone.
What is the skin condition that presents with, painful sterile pustules/ nodules, significant scarring, in groin, chest and inguinal clefts
Hidradentis Suppurativa
Who are the demographic/ occupation most affected by Hidradentis Suppurativa
1)Female
2) All Races
3)Genetic
4)Obesity
5) Stress
6) other factors (smoking drugs hormones)
What is the treatment of Hidradentis Supprativa
1) BPO + Antibacterial Soap
2) Lose weight, reduce friction, oral antibiotics
3) If hormonal, spirolactone, finasteride, metformin
What is the skin condition that present, as a large red bump over gluteal cleft
Pilonidal cyst
Who are the demographic/ occupation most affected by Pilondal Cyst
1) curly hair
2) genetic
3)bad hygiene
4) people who sit to often
5) male
What is the treatment for piliondal cyst
1) No treatment if asymptomatic
2) I & D, excision of abscess
3) refer to gen surgery
4) Pain Management/ oral antibiotics
What is the skin condition that presents with, grey/black velvety texture located in neck, axillae and groin
Acanthosis Nigricans
What is the treatment of Acanthosis Nigricans
1) Treat Underlying issues (glucose and insulin test)
2) Exfoliative cream - Salicylic acid, urea, retinoids
Who are the demographic most affected by Acanthosis Nigricans
1) Diabetic/ insulin resistance
2)obese
3)genetic
What skin condition presents with, Spongiosis in histology, lichenification, IgE response and presents with dry itchy skin
Eczema-atopic Dermatitis
How does eczema present in infants body regions?
Cheeks, perioral, wrists, extensor arms and legs
How does eczema present in Adults body regions?
Hands, Feet, flexural, extensor
What is the treatment for Eczema
1) Protective barrier (stop itching)
2) Antihistamine(Benadryl,Zyrtec, hydrazine)
3) avoid triggers
4) Topical Corticosteroids, glucorticoids, hydrocortisone
What is the skin condition that presents with, Tiny pruritic vesicles on hands and feet (microvasularization) , followed by intense itching and lichenifcation
Dihydrostic Eczema
What is the Treatment for Dihydrostic Eczema
1) Protective barrier (stop itching)
2) Antihistamine(Benadryl,Zyrtec, hydrazine)
3) avoid triggers
4) Topical Corticosteroids, glucorticoids, hydrocortisone
What is the skin condition that presents with abnormal response to normal yeast (malazzezia), effects beard, scalp, eyebrows, and babies cradle cap.
Sebborhic Dermatitis
Who are the demographic most affected by Sebbhorhic Dermatitis
1) Infants
2) Young-middle aged adults
3) old men
4)Psoriasis
What is the treatment for Seborrhea Dermatitis
1) Scalp Treatment ( Ketoconazole Shampoo (2-3x per week)
2)Skin Treatment ( Ketoconazole Cream 2x a day)+ Hydrocortisone or TCIs
What is the skin condition that presents with bilateral swelling in lower legs, that may ulcerate.
Stasis Dermatitis
What is the treatment of Statis dermatitis
1) 2 weeks of medium strength topical steroid (Triamiconolone)-
2) Control edema, compression socks, leg wrapping
What are the two types of contact dermatitis
irritant and allergic
What are commons symptoms seen in irritant dermatitis
Lichenified, Burning, stinging, ISOLATED, scabbing, ulceration
What are common symptoms seen in Allergic Dermatitis
Intense Pruritus, stinging, edema, FEVER (immune mediated)
Treatment for contact dermatitis
ACD: Topical Corticotropin steroid, patch test if unknown, if severe 2 weeks prednisone taper or IM Kenalong
ICD: Remove Irritant, Class 1 corticosteroids, Systemic glucorticoids (2 week taper), Barrier cream
What skin condition presents with, irritated, itchy skin, possible vitamin D deficiency, with a sensitivity to light
Photosensitivity