chapter 10 - leukocyte development, kinetics, and functions

GMP

neutrophils & monocytes are direct descendants of a common progenitor known as

metamyelocyte

stage in neutrophilic development in which the nucleus is indented in a kidney bean shape

cytoplasm has secondary granules that are lavender in color

presence of fewer than 20 primary granules per cell

type II myeloblasts are characterized by

nonspecific destruction of foreign organisms

function of neutrophils

eosinophils and basophils

cells that are important in immune regulation, allergic inflammation, and destruction of tissue invading helminths

IgE

basophils & mast cells have high-affinity surface receptors for which immunoglobulin

monocytes

cell type that is capable of differentiating into osteoclasts, macrophages, or dendritic cells

monocyte degrading antigen & presenting it to lymphocytes

macrophages aid in adaptive immunity by

plasma cell

final stage of B cell maturation after activation by antigen

rearrangement of antigen receptor genes

unique to both B and T lymphocytes and occurs during their early development