Looks like no one added any tags here yet for you.
norepinephrine
adrenaline
serotonin
dopamine
gamma-aminobutyric acid (GABA)
decreased inhibitory signaling
decreased GABA in the brain (family history)
genetic contribution (heritable)
COMT
Adenosine 2A receptor
CCK
CCK Receptor B
5HT2A receptor
Monoamine oxidase-A
treatment of anxiety
treatment of sleep problems (insomnia)
management of epilepsy and seizure disorder
IV agents in anesthesia
sedative and possible amnestic effects during medical or surgical procedures such as endoscopy and bronchoscopy
control of ethanol or other sedative-hypnotic withdrawal states
muscle relaxants in specific neuromuscular disorders
initial management of mania and the control of drug-induced hyper-excitability states
Benzodiazepines
Barbiturates
newer hypnotics, Zolpidem
shortness of breath
chest pain
rapid, fluttering, or pounding heart
azepam
azolam
-azep
Oxazepam (Serax)
Lorazepam (Ativan)
Temazepam (Restoril)
Microsomal oxidation (phase 1)
Metabolite conjugation (phase 2)
Estazolam
Oxazepam
Lorazepam
Nicotinic (ACh) & NMDA (Glutamate) Receptors → Excitatory (Depolarization) → Increase neuron activity
GABAA Receptors → Inhibitory (Hyperpolarization) → Decrease neuron activity
GABA binds to GABAB receptor
Alpha (α) subunit detaches from the G-protein
Alpha subunit binds to the effector
K⁺ (potassium) channels open → K⁺ flows out
Ca²⁺ (calcium) channels close
Neuron slows down (inhibition)
muscarinic acetylcholine receptors
serotonin receptors
histamine receptors
norepinephrine receptors
a1
a2
a3
a5
agonist
antagonists
inverse agonist