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Addition Rule
the probability that any one of two or more mutually exclusive events will occur is calculated by adding together their individual probabilities. ("OR")
Alleles
The different forms of one gene.
Anchorage dependence
the requirement that to divide, a cell must be attached to a solid surface
Apoptosis
Programmed cell death involving a cascade of specific cellular events (starting with a chemical signal) leading to death and destruction of the cell.
Binary Fission
type of asexual reproduction in which an organism replicates its DNA and divides in half, producing two identical daughter cells
both Binary fission and Mitosis produce
genetically identical daughter cells from their respective parent cells
Cell Cycle Control System
A cyclically operating set of molecules in the cell that triggers and coordinates key events in the cell cycle.
Cell Cycle
sequence of events from the production of a eukaryotic cell to the time the cell itself reproduces
Centromere
The region of the chromosome that holds the two sister chromatids together during mitosis
Centrosome
A structure present in the cytoplasm of animal cells that functions as a microtubule-organizing center and is important during cell division. A centrosome has two centrioles.
Chromatin
granular material visible within the nucleus; consists of DNA tightly coiled around proteins
Chromosomal inversion(Chromosomal mutation that occurs during crossing over)
Pieces of DNA that broke off to cross over inert upside down
chromosomal Translocation(Chromosomal mutation that occurs during crossing over)
piece of DNA Goes to the wrong chromosome
Chromosome
condensed threads of genetic material formed from chromatin as a cell prepares to divide
Cleavage [Furrow]
the area of the cell membrane that pinches in and eventually separates the dividing cell
Crossing Over
process in which homologous chromosomes exchange portions of their chromatids during meiosis
Cyclic AMP
Second messenger made from ATP by adenylyl cyclase, inactivated by phosphodiesterase which converts it to AMP
Cyclin dependent kinases
A protein kinase (enzyme) that is active only when attached to a particular cyclin. Cyclin binds to the kinase during interphase and mitosis, triggering and controlling activities during the cell cycle.
Density Dependent Inhibition
cells stop dividing when they come into contact with one another (crowded cells stop dividing)
Dihybrid
Crosses between individuals that differ in two traits (tracking two traits in a cross)
Dominant Allele
An allele whose trait always shows up in the organism when the allele is present. This allele produces more proteins for its trait than its counterpart does
Down Syndrome
a congenital disorder caused by having an extra 21st chromosome (Trisomy 21); results in a flat face and short stature and mental retardation
Genome
the complete genetic material contained in an individual that makes the individual unique
Genomic Imprinting
a phenomenon in which expression of an allele in offspring depends on whether the allele is inherited from the male or female parent.
Heterozygote
when an organism's genotype has dominent and recessive genes for a trait (ex. Bb)
Homozygote
when an organism's genotype has either both dominant genes for a trait or both recessive genes (ex. BB or bb)
Hormone
signal molecule released into the bloodstream that triggers particular responses
how does cytokineses happen in plant cells?
through the formation of a cell plate. This cell plate, a new cell wall, forms between the two newly divided nuclei
How many alleles are in one genetic locus on a chromosome
2 alleles one from the maternal and one from paternal
How many cells are produced in mitosis
2 diploid cells that are genetically identical. They are clones of the parent cell
How many chromosomes do gametes have
23 chromosomes
How many chromosomes do Somatic cells have
46 chromosomes
How many gametes are formed by meiosis
4 for every diploid cell used
How many pairs of Autosomes Do Humans have
22 pairs
How many pairs of SEX CHROMOSOMES do humans have
1 pair
how many sets of chromosomes does a somatic cell contain
2 sets of chromosome that occur in a homologous pair ( one from female and one from male parent)
how many times is DNA replicated in meiosis
once
independent assortment
process that result in more than one possible arrangement of tetrads in metaphse 1
Karyotype
A picture of all the chromosomes in a cell arranged in pairs
Law of Independent assortment
Mendelian principle stating that genes for different traits are inherited independently of each other (genes of one trait don't interfere with genes of another trait)
Law Segregation
Mendel's law that states that the pairs of homologous chromosomes separate in meiosis so that only one chromosome from each pair (each parent) is present in each gamete.
Ligand
A signal molecule that binds specifically to a receptor site of another molecule
Linkage Map
A genetic map based on the frequencies of recombination between markers during crossing over of homologous chromosomes.
Linked Genes
genes located on the same chromosome that tend to be inherited together in genetic crosses
Locus
the specific site of a particular gene on its chromosome
Malignant Tumor
mass of abnormal cells resulting from uncontrolled cancer cell division (can spread throughout the body)
Meiosis is a form of
reductive cell division
Metastasis
spread of cancer cells beyond their original site in the body
Mitotic Spindle
An assemblage of microtubules and associated proteins that is involved in the movements of chromosomes during mitosis.
Monohybrid
genetic crosses that involve one trait
Monosomy
a condition in a diploid cell in which one chromosome of one pair is missing as a result of nondisjunction during meiosis
Multiplication Rule
A rule of probability stating that the probability of two or more independent events occurring together/simultaneously can be determined by multiplying their individual probabilities. ("AND")
nondisjunction
homologous chromosomes fail to separate at anaphase one
or sister chromatids fail to separate in anaphase two
Polyploidy
condition in which an organism has a full extra set of chromosomes
Protein Kinases
Enzymes that activate or inactivate other proteins by adding a phosphate group to them
Protein Phosphatases
An enzyme that removes phosphate groups from proteins, often functioning to reverse the effect of a protein kinase.
Recessive Allele
an allele that is masked when a dominant allele is present
Recombinant Chromosomes
a chromosome created when crossing over combines the DNA from two parents into a single chromosome
Second Messengers
A small, nonprotein, water-soluble molecule or ion, such as calcium ion or cyclic AMP, that relays a signal to a cell's interior in response to a signal received by a signal receptor protein.
Sex-linked gene
a gene located on a sex chromosome
Signal Transduction Pathway
A series of steps linking a mechanical or chemical stimulus to a specific cellular response.
Sister Chromatid
one of a pair of identical chromosomes created before a cell divides
Trisomy
A genetic condition of having three chromosomes instead of two (an extra chromosome).
True Breeding
describes organisms or genotypes that are homozygous for a specific trait and thus always produce offspring that have the same phenotype for that trait (purebreds)
what are 2 types of asexual reproduction
binary fission and mitosis
What are gametes
Reproductive/sex cells
what are Gametes
Sex cells
What are haploid cells?
Haploid cells have only one copy of each chromosome. Gametes are haploid.
What are oncogenes?
mutated proto-oncogenes which do not produce proper proteins to regulate cell cycle
What are protooncogenes?
Genes that code for cell-cycle regulatory proteins
What are Somatic cells
Cells in the body that are NOT reproductive/Sex cells and are not specialized for reproducing
What are the chromosomal mutations that occur during crossing over
-duplication
-deletion
-inversion
-translocation
what are the errors in meiosis
nondisjunction,aneuploidy
what are the two basic strategies of cell reproduction
asexual reproduction and sexual reporduction
What are tumor suppressor genes?
genes for proteins that stop cell division if conditions are not favorable,When mutated cells override checkpoints
What can animals produce to stimulate cell divisions
growth factors
what causes genetic variation in asexual reproduction
Mutations or changes int he dna sequence due to environmental factors or copying errors
what do prokaryotes use to asexually reproduce
Binary fission
what do single cell and multicellular eukaryotes use to asexually reproduce
mitosis
What does centrosome position determine
The plane of cell division
What does sexual reproduction involve?
involves fusion of gamete
What happens in Anaphase of mitosis?
The chromosomes separate forming chromatids and daughter chromsomes move toward the opposite ends of the cell
What happens in Anaphase one of meiosis?
Kinetochore spindle fibers pull tetrads apart and pull chromosomes to opposite ends of the cell
What happens in cytokinesis in animal cells?
Cell forms cleavage furrow actin and myosin form in the inner surface of the membrane and form contractions to pinch the cell in two
What happens in cytokinesis in plant cells?
The cell plate divides the cytoplasm and forms a cell wall
What happens in G1 phase of interphase
The cell gathers nutrients and synthesizes RNA and protiens for DNA Synthesis and Chromosome replication in the S phase
What happens in metaphase of mitosis?
chromosomes line up on metaphase plate. Chromosomes align at the center of the cell and form the metaphase plate.
What happens in metaphase one of meiosis
-kinetochore spindle fibers drag tetrads onto metaphase plate
and line them up
What happens in prometaphase of mitosis?
sister chromatids become attached to the kinetochore (strandy part of the spindle), which are attached to the centrsome, nuclear envelope breaks
What happens in prophase of mitosis
Nuclear Envelope disappears, Chromosomes or condense, mitotic spindle forms and attach to kinetochores.
what happens in prophase one of meiosis
-mitotic spindle begins to form
nuclear membrane begins to break down
synapsis occurs to form tetrads
crossing over occurs to increase genetic variation
What happens in telophase of mitosis?
-chromosomes uncoil
-spindle fibers disintegrate
-nuclear memberane forms
What happens in telophase one of meiosis
nuclear envelope forms around separated chromosomes
chromosomes decondense
nucleolus reappears
What happens in the G2 phase of the interphase?
Cell creates micro tubules for segregating chromosomes and cell checks its DNA for errors
What happens in the S phase of Interphase
DNA is replicated in the S Phase
What is a centrosome?
an organelle near the nucleus of a cell that contains the centrioles (in animal cells) and from which the spindle fibers develop in cell division.
What is a diploid cell?
A cell with two sets of chromosomes
What is a genetic locus
The location of a particular gene on a chromosome
what is a homolog
pair of chromosomes that carry the same genes one from mother and one from father
What is a sister chromatid?
one half of a duplicated chromosome