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Order of meninges layers
epidural space, dura mater (TOUGH), arachnoid mater, (delicate, webish), subarachnoid space, (pia mater (thin/delicate)
denticulate ligaments
extensions of pia mater that secure cord to dura mater
filum terminale
extension of pia mater that anchors spinal cord
definition of meningitis
Inflammation of the pia arachnoid of brain, spinal cord or both
clinical signs of meningitis
fever, headache, nuchal rigidity, kernig's sign
how do you test for meningitis?
test of CSF look at glucose, proteins, lymphocytes
what levels are increased with bacterial meningitis?
lymphocyte levels
what is viral/aseptic meningitis caused by?
herpes/epstein bar, newborn e coli., influenza
kernigs' sign what is it and what is it used to test?
meningitis, knee and hip 90° in supine lying position, extension of knee is painful or limited in extension (neck pain will worsen with knee extension)
brudzinski sign what is it and what is it used to test?
meningitis, supine position, bending neck/passive flexion of neck causes knee and hip flexion
epidural hematoma is shaped like what on an x-ray?
LEMON
What is epidural hematoma?
Bleeding in epidural space (between skull and dura mater)
what is epidural hematoma caused by?
skull fracture
Symptoms of epidural hematoma
Headache - intracranial pressure, altered mental state, confusion, nausea, lucid interval - seem normal for a little bit then go back
subdural hematoma is shaped like what on an x-ray?
banana
what is subdural hematoma caused by?
bleeding between Dura mater and arachnoid mater
What causes acute subdural hematoma?
Sudden impact or tearing of vessel - traumatic brain injury
What causes chronic subdural hematoma?
Slow onset, overtime - leakage of blood vessel, shrinkage due to aging - also could be anticoagulants, long-term alcoholics, common cause of dementia
*lose function very slowly overtime
describe how cerebral spinal fluid flows through the brain
Lateral ventricles, third ventricle, cerebral aqueduct, fourth ventricle, connecting foramina
What is CSF?
Ultra filtered blood, cushions and protects CNS from trauma, nourishes CNS
Where is CSF produced?
choroid plexus
What is lumbar puncture/spinal tap usually done?
L3 vertebrae, after spinal cord has ended
Why is a lumbar puncture/spinal tap done?
Withdraw of CSF to test if meningitis is bacterial or viral
What is hydrocephalus?
Too much water pressure on the brain, too much CSF pressing on CNS tissue due to overproduction or decreased reabsorption
what are some symptoms of hydrocephalus?
enlarged ventricles, known in newborn before birth - eyes look downward, loss of bladder/bowel control - immediate medical condition sudden means problem with CNS
Obstructive hydrocephalus
tumor formation
non-Obstructive hydrocephalus
Faulty reabsorption, removal of part of choroid plexus in lateral ventricle
where does blood supply to the brain come from?
internal carotid (85%) and vertebral arteries (15%)
Vessels drain water from the brain?
Internal jugular vein, external jugular vein
anterior cerebral artery supplies
frontal and parietal lobes (superior and medial)
Middle cerebral artery supplies
frontal, temporal, and parietal lobes (lateral)
Posterior cerebral artery supplies
temporal and occipital lobes
vertebral arteries come together to form
basilar artery
cerebellar arteries supply the
cerebellum
Functional significance of circle of Willis
Allows multiple choice selection for blood flow to the brain
What feeds into dural sinuses?
venous, also where CSF goes
dural sinuses join to eventually form the internal jugular vein
anoxia
Decrease oxygen but blood still circulates
ischemia
Loss of blood flow due to cardiac/vascular causing decreased oxygen
TIA
small stroke that last a few moments and symptoms go away
what is a stroke?
Sudden onset of neurological deficits due to disruption of blood supply to the brain - cause permanent damage to brain tissue
FAST- describe symptoms of a stroke
face, arms, speech, time
Numbness/weakness of face, arm, leg
Trouble speaking/walking
Trouble seeing, dizziness, loss of balance/coordination, severe headache with no known cause
severe headache is more common in which type of stroke
hemorrhagic (rupture/increased pressure)
Stroke symptoms in women
Face, arm, leg pain, hiccups, nausea, chest pain/palpitations
thrombus
stationary blood clot
embolus
moving blood clot
what is the most common stroke?
ischemic stroke
What does recovery look like for ischemic stroke?
Recovery is dependent on damage/how long the blockage was allowed to occur - weeks to years
When do signs come on for ischemic stroke?
One by one or all at once
Treatment for ischemic stroke
Thrombolytics, anticoagulants or surgery for treatment
Where do most ischemic strokes occur?
Middle cerebral artery
Which stroke has highest rate of death but is the least common?
intracerebral hemorrhagic stroke
What is the cause of intracerebral hemorrhagic stroke?
Chronic high blood pressure
What is a common symptom of intracerebral hemorrhagic stroke?
First symptom severe headache - 50% - often during activity
What does recovery look like for intracerebral hemorrhagic stroke?
If survive usually never recover
What is treatment like for intracerebral hemorrhagic stroke?
Don't want person to have anticoagulant, given very large infusions of vitamin K which is essential for blood clotting
subarachnoid hemorrhagic stroke is how common?
3%
What is the most common cause of subarachnoid hemorrhagic stroke?
Ruptured aneurysm
Symptoms of subarachnoid hemorrhagic stroke?
Sudden severe headache - thunder clap peaks within seconds, followed by brief loss of consciousness, face pain and vision issues - think about where optic nerve is located
Treatment for subarachnoid hemorrhagic stroke?
Surgery
subarachnoid hemorrhagic stroke is more common in...
women
not a stroke if its from
head injury
survival rate of subarachnoid hemorrhagic stroke?
Half day before reaching the hospital, severe impairments become permanent