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Acetylcholine (ACh)
Enables muscle action, learning, and memory. If ACh-producing neurons deteriorate (as in Alzheimer's disease), there are impairments.
Dopamine
Influences movement, learning, attention, and emotion. Oversupply is linked to schizophrenia. Undersupply causes tremors and decreased mobility in Parkinson's disease.
Serotonin
Affects mood, hunger, sleep, and arousal. Undersupply is linked to depression; drugs that raise serotonin treat depression.
Norepinephrine
Helps control alertness and arousal. Undersupply can depress mood.
GABA (gamma-aminobutyric acid)
A major inhibitory neurotransmitter. Undersupply linked to seizures, tremors, and insomnia.
Glutamate
A major excitatory neurotransmitter; involved in memory. Oversupply overstimulates the brain, causing migraines or seizures.
Endorphins
Neurotransmitters that influence pain or pleasure perception. Oversupply with opioid drugs can suppress the body's natural endorphin supply.
Substance P
Involved in pain perception and immune response. Oversupply can cause chronic pain.