epigenetics
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5 Terms
what is the definition of epigenetics?
a heritable change in gene function without change to the base sequence if DNA
what is a chromatin?
the combination of DNA and histones
the chemical layer that surrounds the chromatin is called…
the epigenome
how does increased methylation of DNA affect DNA transcription?
involves addition of a CH3 group to cytosine bases which are next to guanine
prevents transcription factors from binding, suppressing transcription
how does decreased acetylation of DNA affect DNA transcription?
positively charged histones are positively charged bind to negatively charged DNA
decreasing acetylation increases positive charge of histones
binding becomes too tight and prevents transcription factors from accessing DNA, suppressing transcription
Note 
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