AP Bio - Unit 4: Cell Communication

studied byStudied by 0 people
0.0(0)
Get a hint
Hint

Local Signaling

1 / 29

30 Terms

1

Local Signaling

Adjacent Cells, Direct Contact, Local Regulators (aka signal molecules or ligands)

New cards
2

Paracrine Signaling

Secretory vesicles sending signals to a target cell

New cards
3

Synaptic Signaling

Nerves sending a signal to a target cell

New cards
4

Endocrine Glands

Send hormones to the target cell through the blood stream

New cards
5

Signal Reception

Ligands match the shape of the protein receptors on the target cell and bind together

New cards
6

Signal Transduction

Ligand changes shape and the phosphorylation cascade occurs

New cards
7

Kineses

Enzyme that removes a phosphate from ATP and puts them on another molecule

New cards
8

Cellular Response

Final activated protein from a phosphorylation cascade goes into the nucleus and binds to a gene on DNA that turns the gene “on” or “off”

New cards
9

Steroid Hormones

Bind to intracellular receptors

New cards
10

G-protein-linked receptors

G-protein as a peripheral protein because GTP (guanosine triphosphate) is used instead of ATP for the first step of the phosphorylation cascade, the rest use ATP

New cards
11

Tyrosine Kinase Receptors

Come in pairs with phospholipids between them; separately tagged by their own ligands, move together in the plasma membrane and snap together; phosphorylated with ATP to give energy to the molecule; proteins attach to relay a cellular response

New cards
12

Ion (Gated) Channel Receptors

Signal molecule opens the gate for ions to flow through

New cards
13

Phosphorylation Cascade

A series of protein kinases add a phosphate to the next one in line, activating it; phosphate enzymes then remove the phosphates

New cards
14

Cyclic AMP (cAMP)

Made from ATP; can bind to a protein receptor on ER or other organelles; acts as a second messenger in cellular pathways to initiate phosphorylation cascade

New cards
15

Adenylyl Cyclase

Enzyme that breaks off the first two phosphates to create cAMP for it to act as a second messenger

New cards
16

Phosphodiesterase

converts cAMP to AMP

New cards
17

Inositol Triphosphate (IP3)

Can trigger an increase in Ca+2 in the cytosol

New cards
18

Phospholipase C

Breaks off IP3 from PIP2, leaving DAG behind

New cards
19

Pathway Branching

One peripheral protein tags multiple relay molecules

New cards
20

Cross-Talk

Occurs when one peripheral protein tags a relay molecule that was in the path of a different peripheral protein, either activating or inhibiting it

New cards
21

Scaffolding Proteins

Can increase the signal transduction efficiency by allowing multiple other proteins to attach

New cards
22

Saltatory Conduction

Opening sodium ion gates at the nodes of Ranvier

New cards
23

Simple Endocrine Pathway

Catalyzed by a protein (no nerves) → hormone

New cards
24

Simple Neurohormone Pathway

Catalyzed by a sensory neuron → gland → hormone

New cards
25

Simple Neuroendocrine Pathway

Catalyzed by a sensory neuron → endocrine gland #1 → hormone #1 → endocrine gland #2 → hormone #2

New cards
26

The Master Glands

Control other endocrine glands (hypothalamus, pituitary gland)

New cards
27

Glucagon

Secreted by alpha cells in the pancreas; raise blood glucose levels by converting glycogen to glucose and stimulating the breakdown of fat and protein into glucose

New cards
28

Insulin

Bonds to body cells, telling them to pick up glucose (liver cells store it in chains as glycogen)

New cards
29

Glycogen

Chains of glucose

New cards
30

Local Regulators

Neurotransmitters, cytokines and growth factors, nitric oxide, prostaglandins

New cards

Explore top notes

note Note
studied byStudied by 24 people
... ago
5.0(1)
note Note
studied byStudied by 15 people
... ago
5.0(1)
note Note
studied byStudied by 34 people
... ago
5.0(1)
note Note
studied byStudied by 3 people
... ago
5.0(1)
note Note
studied byStudied by 13 people
... ago
5.0(2)
note Note
studied byStudied by 20 people
... ago
5.0(1)
note Note
studied byStudied by 30 people
... ago
4.0(1)

Explore top flashcards

flashcards Flashcard (52)
studied byStudied by 11 people
... ago
5.0(1)
flashcards Flashcard (55)
studied byStudied by 2 people
... ago
5.0(1)
flashcards Flashcard (73)
studied byStudied by 2 people
... ago
4.0(1)
flashcards Flashcard (21)
studied byStudied by 9 people
... ago
5.0(1)
flashcards Flashcard (46)
studied byStudied by 9 people
... ago
5.0(1)
flashcards Flashcard (29)
studied byStudied by 1 person
... ago
5.0(1)
flashcards Flashcard (33)
studied byStudied by 7 people
... ago
5.0(2)
flashcards Flashcard (104)
studied byStudied by 2 people
... ago
5.0(1)
robot