Animation Assessment: DNA Replication

BIOL 1020 Rebecca Riggs

What is the first thing to occur in DNA Replication?

the strands of the DNA double helix are separated

Which of the strands uses a template for DNA replication?

both strands use a template during DNA replication

On which strand are new nucleotides being added continuously in the same direction as the replication fork is opening?

the leading strand

On which strand is DNA synthesis discontinuous, occurring in fragments that are later connected?

the lagging strand

Which statement about DNA replication is true?

when DNA polymerase reaches a primer from prior DNA synthesis, the primer is moved and replaced with DNA nucleotides

RNA primase lays down an RNA primer to start DNA replication. If a mutation occurs that blocks the function of RNA primase, which synthesis of which strand is affected, and why?

both strands are affected because all DNA polymerase can only add new nucleotides to a 3’-OH present at the end of the RNA primer