Postpartum Meds

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OB/LD CU NSG 3010

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14 Terms

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Cytotec (misoprostol)

  • Prostaglandin

  • Postpartum hemorrhage (uterine atony)

  • Rectal, PO, Sublingual

  • Contraindications & Cautions

    • Not be used to prevent NSAID-induced gastric injury due to potential for fetal harm or death. May cause severe diarrhea in the nursing infant. Hypersensitivity to prostaglandins.

  • Side effects

    • Abd. pain

    • Diarrhea

    • Miscarriage

    • Constipation

    • Dyspepsia

    • Flatulence

    • N/V

    • Menstrual disorders

    • HA

  • NSG considerations

    • educate pt on side effects

    • Not 1st or 2nd line treatment

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Lysteda (transexamic acid/TXA)

  • antifibrinolytic agent

  • postpartum heorrhage

  • IV

  • Considerations & Cautions

    • thromboembolic disoders

    • acquired defective color vision

    • Caution

      • renal impairment

      • hematuria

      • use of hormonal contraceptive

  • Side effects

    • HA

    • pain

    • seizures

    • anaphylaxis (PO usually)

    • visual abnormalities

    • HoTN

    • thromboembolism

    • N/V/D

  • NSG Consisderations

    • give first few hours after delivery to inhibit enzymatic breakdown of fibrin blood clots

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Methergine (methylergonovine)

Uterine stimulant (oxytocic) 

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Methergine (methylergonovine)

Postpartum Hemorrhage: Stimulates sustained/tetanic contraction of the uterus 

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Methergine (methylergonovine)

Avoid if patient has elevated blood pressure

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Methergine (methylergonovine)

Raises patient BP/HTN, 

Stroke, N/V, cramps 

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Methergine (methylergonovine)

Common second choice drug for uterine atony 

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