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Exam 2
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What is health psychology?
a field within psychology that studies how psychological, social, and biological factors influence health and illness
is relatively new, and it was developed in part as a function of the fact that most of the top 10 causes of death in the US are lifestyle diseases
Adolescent deaths _____ ____% between 1935-1985 due to ________
dropped 90%
due to vaccines
Top 10 causes of death are ______ related
lifestyle
What are health defeating behaviors ?
smoking, not exercising or not sleeping/eating
What is the Illusion of Invulnerability?
individuals underestimate the probability of something bad happening to them
the false belief that one is safe from danger or misfortune
A child believes they wont get caught when stealing a cookie, what is this an example of?
Illusion of Invulnerability
What is someone who is Optimism Bias?
thinks bad things happen to other people but not them
ENgels 1977 Science Article and the acknowledgment that _______ factors alone could not account for illness
Biological
What is the biopsychosocial model of health psychology?
a holistic model that considers biological, psychological, and social factors in health and illness
Placebo effect is when?
an individual experiences the positive effects of a medication/supplement/surgery that they expect to get
works in sham surgeries
there are institutes to study it
Nocebo Effects is when
the individual experiences unwelcome side effects
where is nocebo most common?
in disorders with emotional bend to them (pain and depression)
What matters during the placeo effect?
color of the pill ( yellow is considered the most “effective )
price ( a $1.00 pill has more of an effect than one costing $0.25 yet they are the exact same medication )
If a placebo “pain cream” is administered, an _______ measures brain activity, you will see the release of our own _______ in certain brain areas
MRI
Pain Killers (endorphins)
What is the Federal Law for pills?
the active ingredient has to be the same in NAME and GENERIC brands
What is Classical Conditioning?
it plays a role, combined with expectancy
a type of learning where a neutral stimulus (like a sound) becomes associated with a naturally occurring stimulus (like food), causing the neutral stimulus to eventually trigger a response (like salivation) on its own
Who introduced the experimental field of stress physiology?
Hans Selye
What did Hans Selye develop?
GAS
General Adaptations Syndrome
What are stressors of the General Adaptations Syndrome?
cold, heat or even electric shock
What are the 3 stages of GAS
Alarm: bells go off ( body is thrown out of wack) and it senses something is wrong
Resistance or Adaptation: stress response and the return to homeostasis
Exhaustion: If the stress continues, you start to run out of the good things in your body. ( can lead to depression or chronic fatigue)
What are the two branches of the autonomic nervous system
Sympathetic and Parasympathetic
The half of the brain that is turned ON is called
Sympathetic Nervous System
Where does the sympathetic nervous system originate from?
in the brain and then it goes through the spine and exits to branch out to nearly ever organ, blood vessel and blood gland in your body.
What are important neurotransmitters for sympathetic arousal?
Epinephrine, Dopamine, and Norepinephrine.
What does NE, E, and DA do in the brain?
turn ON amygdale and OFF the prefrontal cortex
What half of the brain is turned OFF in the autonomic nervous system?
Parasympathetic Nervous System
What does the parasympathetic nervous system do?
mediates calm and vegetative activities
Its primary role is to promote relaxation and digestion, also known as the "rest and digest" response
What is the classic stress hormone
cortisol
What are glucocorticoids
stress hormone
released from HPA
class of steroid hormone
great for mobilizing energy
short term : immune enhancing
long term: immune suppressive
What is cortisol?
classic stress hormone ( peak is 20 minutes after stressor happens )
What is also released during stress?
Glucagon, Prolactin, ADH and endorphins/enkephalins
What are reproductive hormoones
estrogen and testosterone
What is the growth hormone
insulin
Glucagon breaks down?
glucose
ADH is what makes you ________
pee
antidiuretic hormone
What is prolactin
suppresses reproduction
What is an important caveat concerning the stress response
psychological context matters
2 exact stressors may cause different responses
determined to a large part by how a stressor is appraised (primary) and coping possibility (secondary)
The examined HPA response ?
cortisol responds as as result of appraisal of stressor
Appraisal Matters
how you view a stressor totally determines your physiological response
What are the most common HEART ATTACK symptoms in WOMEN
extreme fatigue, lightheadedness/dizziness, neck and jaw pain (could be without chest pain), upper back pain, shortness of breath, chest pressure, vomiting/nausea, feeling of heartburn/indigestion, and discomfort/tigning in one or both arms
What are the most common HEART ATTACK symptoms in MEN
sudden cold sweat, discomfort/tingling in the back/shoulders/arms/neck/or jaw, chest pain/pressure, shortness or breath and nausea
what kind of stress response is very important?
Cardiovascular
In the heart, the top is _____ → _______ and the bottom is the ________ → ________
atria → veins
ventricles → arteries
Right side of the heart pumps blood through the ______.
lungs
Left side of the heart pumps blood to the __________.
peripheral organs
Systole
force of blood leaving
Diastole
force of blood returning
Whats important for survival
blood with its energy source needs to be more available to places that need it
Arteries to your _______ dilate so more blood is available and _______ (decreased flow) to places like your gut and you can also see decreased blood flow to ________.
muscles
constrict
kidneys
What is Chronic Stress
case of stressors your system works exactly like you want
a prolonged state of mental and physical strain that persists over an extended period
what system is #1 on the bad effects list from chronic stress?
Cardiovascular System
what can you think of your heart and blood vessels as?
heart as a pump and your blood vessels as a hose.
use them too much too forcefully, they’ll wear out.
What are steps of Stress-Related Diseases
Hypertension, Left Ventricular Hypertrophy, Bifurcation, Atherosclerosis Plaque, CRP, Thrombus, Angina Pectoris, and Ulcers
What is it called when your blood pressure is chronically high ?
Hypertension (stress raises blood pressure)
What can increase your chance for an irregular heart beat?
left ventricular hypertrophy
a condition where the left ventricle, the main pumping chamber of the heart, becomes thickened and enlarged
What is Bifurcation?
division of something into two branches or parts, and blood vessels undergo this
no cell in your body is more than 5 cells from a blood vessel
How much body mass does the circulatory system take up?
3%
What is the buildup of fatty deposits, cholesterol, calcium and other substances on the inner lining of the arteries?
Atherosclerosis Plaque
it can narrow the arteries and reduce blood flow to vital organs
What is CRP
C-Reactive Protein
a protein produced in the LIVER in response to inflammation to the body but this protein is nonspecific.
What is a better predictor of Cardiovascular disease then cholesterol?
CRP
What is a clot called?
Thrombus
What happens when thrombus clogs up a coronary artery?
heart attack
What happens when thrombus clogs up a vessel in the brain?
stroke
What is it called when you have chest pain/discomfort due to the heart muscle not receiving enough oxygen rich blood?
angina pectoris
might occur due to stress
What characteristics does the immune system have?
the ability to differentiate self from non-self and to exhibit specificity and memory
What are the two main cells in the immune system?
T cells
B cells
Macrophages
What are the two types of T cells
Helper and Cytotoxic
What do Helper T Cells Do?
help with all of kinds of immune responses
includes those caused by antigen (flu virus or developed cancer by your own cells)
help cytotoxic T cells
What do Cytotoxic T Cells do?
help with your own cells becoming altered due to cancer
directly destroy infected cells
What is a macrophage
they do just about everything on their own
destroy some antigens and help T/B Cells combat them as well.
What is PNI?
psychoneuroimmunology
Who started PNI ?
behavioral psychologist Dr. Ader who was studying classical conditioning at the time
Can you condition immune responses?
YES
There is neural innervation of immune tissue
On immune cells there are receptors for E, NE DA and Cortisol
Immune cells produce all of these chemicals as well
What is released as a part of the stress response and can affect your immune system?
Epinephrine, Norepinephrine, ect and Cortisol
Was research able to determine that stress will make you sick ?
yes
What are the important studies in PNI
Rats and control
Girl with lupus
PNI Study Rats and Control
control of a stressor to led to a significant decrease in susceptibility to cancer
PNI study Girl with Lupus
compound CS, every 3 months 1 time Cytoxan, 2 Saline
at end of year she had 4 Cytoxan as opposed to 12 exposures to Cytoxan.
What is autoimmunity?
the result of an overactive immune system
Does stress suppress the immune system ?
yes
Why is stress NOT good?
because the cortisol hormone works differently centrally as opposed to peripherally
How does chronic stress causes cardiovascular disease
stress response causes sympathetic arousal, including increases in heart rate and blood pressure
What is the first step in CVD resulting from Chronic Stress?
hypertension (high blood pressure)
its more complicated then increase in BP from sympathetic activation (fight or flight)
Chronic stress causes high blood pressure leading to?
high blood pressure : due to your blood forcefully pushing through your veins to your heart. When chronic stress happens …
smaller blood vessels have difficulty in controlling the gushing blood so develop muscle to help have better control
What is vascular resistance?
inability for freely flowing blood
can lead to a PERMANENT INCREASE in blood pressure
left ventricular hypertrophy is
enlargement of the heart leading to irregular heartbeat
also there might not be enough blood available for the bigger heart
blood is slamming into the left ventricle (blood returns to heart)
What is the development of plaques due from?
the development of small tears in points of bifurcation in the cardiovascular network.
What do plaques do?
narrow the vessel making blood more hindered
What happens when the plaque breaks off
THRMOBUS (clot)
what is hyperphagic
overeating
stress makes 2/3 of people develop this
stress eat
True or False: Is cortisol an appetite suppressant?
true
Once cortisol is released, what happens?
stimulates appetite
makes us hungry for starchy, sugary, fatty foods.
What else does cortisol do, other then increasing appetite?
increases the storage of that food by causing fat cells to produce an enzyme that breaks down the circulating nutrients into their storage forms
Nutrients are stored in ______ cells
fat cells
Visceral Fat Cells are
fat cells around your belly leading to the “apple” shape
Gluteal Fat Cells are
fat cells around your rear leading to the “pear” shape
Where does cortisol stimulate fat deposition?
abdomen (promotes the apple shape)
True or False: Abdominal fat cells are less sensitive to cortisol?
false
they are more sensitive because they have more receptors that respond to them and activate those fat storing enzymes
Having too much visceral fat (apple shape) is at more risk for ?
cardiovascular disease and metabolic disorder because fat released from those cells more readily find its way to the liver