Quiz 2 Antidabetic and Cholestrol Mechanisms etc..

Dapagliflozin

• farxiga

• subclass: SGLT2

• treats diabetes, HF, and chronic kidney disease

• can cause hypoglycemia and UTI

Ezetimibe

• zetia

• antihyperlipidemic

• class: cholestrol absorption inhibitor

• subclass: NPCIl1 antagonist

• treats cholestrol

• can cause constipation, diarrhea, headache, nausea

Glimepiride

• amaryl

• second-gen sulfonylurea

• treats diabetes type 2

• causes hypoglycemia, nausea, headache

glipizide

• glucatrol

• second-gen sylfonylurea

• treats diabetes

• last line

insulin human

• humulin R or novolin R

• subclass: short acting

• treats diabetes type 1 and 2

liraglutide

• victoza, saxenda

• glucagon-like peptide 1 receptor (glp1) agonist

• treats diabetes 2 and obesity

lovastatin

• altoprev

• treats cholestrol and CHD

metformin

• glucophage

• biguanide class

• treats type 2 diabetes

• decreases hepatic glucose production and enhances glucose usage by muscles

pioglitazone

• actos

• class: thiazolidinedione

• treats type 2 diabetes

• increases risk of CHF and bladder cancer

pravastatin

• pravachol

• Class: HMG-CoA Reductase inhibitor

• treats cholestrol, heart attack, and strokes

rosuvastatin

• crestor, ezallor

• Class: HMG-CoA reductase inhibitor

• treats cholestrol and CVD

Simvastatin

• zocor

• Class: HMG-CoA reductase inhibitory

• Treats cholestrol and CVD

Atorvastatin

• lipitor

• HMG-CoA Reductase inhibitor

• treats cholestrol and CVD

sitagliptin

• januvia

• class: dipeptidyl Peptidase-4 inhibitor

• antidiabetic

• treats type 2 diabetes

fenofibrate

• antara

• fenoglide

• class: fibrate

• indication: decrease TG fats and cholesterol

gemfibrozil

• lopid

• class: fibrate

• don’t use statins with it

dulaglutide

• januvia

• class: GLP1

• injection

semaglutide

• ozempic; wegovy

• class:GLP 1 agonist

• injection

• treats t2dm and weight loss

empagliflozin

• jardiance

• treats t2dm; HF; chronic kidney disease

• has renal and cardiovascular benefits

• SGLT2 inhibitor

patient consultation for insulin

• inject into the upper thigh/arm/abdomen 30 minutes before eating

• change needles every time

• rotate injection sites

• unopened vials in the fridge

• if painful, open in room temperature

• monitor blood sugar two-4 times a day

• if <70 mg/dL, eat sugar

insulin glargine

• lantus or basalgar kwik pen

• long acting

insulin aspart

• novolog

• rapid acting

insulin lispro

• humalog

• rapid acting

insulin degludec

• tresiba

• long acting

insulin isophane human NPH

• humalin/Novolin 70/30

• intermediate acting