Organic chemistry synthesis pathways

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38 Terms

1
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Alkene to Alkane,

Reagents, Conditions, Name of reaction

H2, Nickel catalyst, 150C Hydrogenation/Addition

2
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Alkane to halogenoalkane

, Reagents, Conditions, Name of reaction

X2, UV light, Free radical substitution

3
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Halogenoalkane to Amine

, Reagents, Conditions, Name of reaction

Conc. ammonia, Heat in a sealed tube, Nucleophilic substitution

4
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Halogenoalkane to Nitrile

, Reagents, Conditions, Name of reaction

KCN in ethanol, Reflux, Nucleophilic substitution

5
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Nitrile to Carboxylic Acid

, Reagents, Conditions, Name of reaction

Dilute HCl and water,Heat, Reflux, Acidic Hydrolysis

6
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Carboxylic Acid to Acyl chloride

, Reagents, Conditions, Name of reaction

SOCl2, . Substitution/halogenation

7
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Acyl Chloride to Carboxylic Acid,

Reagents, Conditions, Name of reaction

H2O, Hydrolysis/nucleophilic addition-elimination

8
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Acyl Chloride to primary amide

, Reagents, Conditions, Name of reaction

Conc. NH3, nucleophilic addition-elimination

9
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Nitrile to Amine

, Reagents, Conditions, Name of reaction

H2, Ni catalyst , Reduction

10
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Acyl Chloride to Ester,

Reagents, Conditions, Name of reaction

Alcohol, esterification

11
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Alkane to alkene,

Reagents, Conditions, Name of reaction

Zeolite catalyst, Heat, Cracking

12
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Halogenoalkane to alcohol,

Reagents, Conditions, Name of reaction

Aqueous NaOH , Nucleophilic substitution

13
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Alkene to Poly(alkene),

Reagents, Name of reaction

Alkene, Addition Polymerisation

14
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Acyl Chloride to secondary amide

, Reagents, Conditions, Name of reaction

Primary Amine, Reflux, Nucleophilic substitution

15
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Alkene to Halogenoalkane,

Reagents, Conditions, Name of reaction

HX gas phase, Room temp, Electrophilic addition

16
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Alkene to alcohol,

Reagents, Conditions, Name of reaction

Steam, conc H3PO4 catalyst, Addition/hydration

17
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Alcohol to alkene,

Reagents, Conditions, Name of reaction

Conc. H3PO4, Heat, Elimination/dehydration

18
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1° alcohol to aldehyde,

Reagents, Conditions, Name of reaction

Acidified potassium dichromate (VI), Simple distillation, Oxidation

19
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Aldehyde to 1° alcohol,

Reagents, Conditions, Name of reaction

NaBH4, Reduction

20
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Aldehyde to carboxylic acid,

Reagents, Conditions, Name of reaction

Acidified potassium dichromate (VI), Reflux, Oxidation

21
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1° alcohol to carboxylic acid,

Reagents, Conditions, Name of reaction

Acidified potassium dichromate (VI), Reflux, Oxidation

22
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Carboxylic acid to 1° alcohol,

Reagents, Conditions, Name of reaction

NaBH4, Reduction

23
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2° alcohol to ketone,

Reagents, Conditions, Name of reaction

Acidified potassium dichromate (VI), Reflux, Oxidation

24
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Ketone to 2° alcohol,

Reagents, Conditions, Name of reaction

NaBH4 , Reduction

25
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Carboxylic acid to ester,

Reagents, Conditions, Name of reaction

Alcohol, conc. H2SO4 (catalyst), reflux, Esterification

26
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Ester to carboxylic acid,

Reagents, Conditions, Name of reaction

dilute acid, Heat, Hydrolysis

27
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Alcohol to Ester, Reagents,

Conditions, Name of reaction

Carboxylic acid, conc. H2SO4 OR acid anhydride , Esterification

28
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Aldehyde to hydroxynitrile,

Reagents, Name of reaction

H+/NaCN(aq),Nucleophilic addition

29
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Ketone to hydroxynitrile,

Reagents, Name of reaction

H+/NaCN, Nucleophilic addition

30
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Nitrile to carboxylic acid,

(Acidic hydrolysis), Reagents, conditions

HCL & H2O heat

31
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Polyesters,

Reagents, Name of reaction

Dicarboxylic acid & diol, Condensation polymerisation

32
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Benzene to cyclohexane,

Reagents, Conditions, Name of reaction

H2, Ni catalyst, High temperature and pressure, Hydrogenation

33
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Benzene to bromobenzene,

Reagents, Conditions, Name of reaction

Br2/aluminium chloride catalyst (halogen carrier), Reflux, Bromination

34
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Benzene to nitrobenzene,

Reagents, Conditions, Name of reaction

Conc. nitric and sulphuric acid, Warm, Nitration

35
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Benzene to methylbenzene,

Reagents, Conditions, Name of reaction

Choromethane & AlCl3 (catalyst), Anhydrous, Friedel-Crafts alkylation

36
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Benzene to phenylethanone,

Reagents, Conditions, Name of reaction

Ethanoyl chloride & AlCl3 (catalyst), Anhydrous, Friedel-Crafts acylation

37
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Phenol to 2,4,6-tribromophenol,

Reagents, Conditions, Name of reaction

Bromine water, Room temp, Bromination

38
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Polyamides,

Reagents , Name of reaction

Dicarboxylic acid & diamine, Condenstaion polymerisation