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clock face test
which test was able to correctly identify the condition Susannah Cahalan was suffering from?
encephalitis (anti-NMDAR)
what condition was Susannah Cahalan suffering from, causing her wide array of symptoms?
neurons
these brain cells transmit information
glia
these brain cells act as support
circuit
neurons are organized with a precise order to act as a ________
roundworm
this was the in-class example with the most simple NS, with only 302 neurons
sea slug
this was the in-class example with the second fewest amount of neurons, only 18,000
gill/siphon withdraw reflex
the sea slug has enough neurons that it is capable of this reflex
rat
this animal has the second most neurons, 50 mil, and the ability for much more complex functions
80
humans have _____ billion neurons
Camillo Golgi
this scientist discovered the staining technique to visualize an entire neuron, but thought neurons all connected (like tubing)
Ramon y Cajal
this scientist used Golgi’s method to look at neurons, but concluded that neurons came close together but did not actually touch
neuron doctrine
each neuron is an independent unit and information must be transmitted through the gaps (synapses)
shapes
Golgi staining revealed neurons can come in an assortment of _______
dendrite, cell body, axon, axon terminal
the general flow of information down a neuron
dendrites
these are the branches off the input zone of a neuron
spines
these are mushroom shaped projections off dendrites
soma
the cell body is also called this
integration
the cell body acts as the _________ zone
axon hillock
area of the neuron that determines whether an action potential is generated
conduction
the axon can be considered the ______ zone
retrograde
_________ transport moves material from the terminal towards the cell body
anterograde
_________ transport moves material from the cell body towards the terminal
anterograde
despite materials being able to go both ways, signals can only travel one way down a neuron. Which type of transport also runs in this direction?
output
the axon terminal could also be considered the ________ zone
chemical, electrical
signaling is ______ between neurons and ______ within a single neuron
cleft
the synaptic terminal releases chemical signals into the synaptic ______
astrocytes
these are the star-shaped glial cells
astrocytes
these glial cells monitor the neuron environment and help form the blood-brain barrier by tiling blood vessels
astrocytes
these glial cells are responsible for responding to brain injury
tripartite synapse
regulation of synaptic signaling between two neurons mediated by an astrocyte, relates to NT recycling
oligodendrocytes
these glial cells wrap myelin on axons in the CNS
schwann cells
these glial cells wrap myelin on axons in the PNS
microglia
these glial cells are referred to as the brain immune system, going to sites of injury and acting similar to a macrophage
structure = function
theme underlying this course and anatomy as a whole
central
this part of the nervous system contains the brain and spinal cord
peripheral
this part of the nervous system contains everything but the brain and spinal cord
nerves
bundles of axons in the PNS
ganglia
clusters of neuron cell bodies throughout body (often near spine or near organs)
somatic
this division of the PNS is responsible for communicating sensory nerves to the CNS (voluntary movement)
autonomic
this division of the PNS is responsible for communicating internal organ messages to the CNS (involuntary movement)
sympathetic
this division of the autonomic NS is responsible for fight or flight
norepinephrine
sympathetic NS main NT
parasympathetic
this division of the autonomic NS is responsible for relaxation and the body at rest
acetylcholine (ACh)
parasympathetic NS main NT
enteric
this division of the autonomic NS is responsible for the gut/digestion
cervical, thoracic lumbar, sacral, coccygeal
the vertebrae from the top of the body down follow this order:
31
how many pairs of spinal nerves are there?
sagittal
the spinal nerves serve each half of the body respectively on a _____ plane
dorsal root ganglion
this transmits information from the sensory nerve to the spinal cord
ventral root
this transmits the signaled response from the spinal cord to the muscle
interneurons
this type of neuron helps transmit info b/w the dorsal root ganglion and the ventral root
sulcus
grove in cerebral cortex
gyrus
matter between two groves on the brain
frontal, parietal, occipital, temporal
4 lobes of the cerebral cortex
longitudinal fissure
this separates the two hemispheres of the brain
central sulcus
this separates the frontal and parietal lobes
sylvan fissure
this separates the parietal lobe from the frontal
optic chiasm
x-shaped feature on the bottom of the brain towards the back of the frontal lobe
olfactory bulb
area sticking towards front of frontal lobe on the bottom of the brain
grey
_______ matter is made of cell bodies and dendrites
white
_______ matter is made of axons with white myelin sheath
corpus callosum
axon tract joining the two brain hemispheres
frontal
this lobe of the brain is responsible for movement and higher-level cognition
parietal
this lobe of the brain is responsible for the body’s sensory info, touch
temporal
this lobe of the brain is responsible for hearing and smell
occipital
this lobe of the brain is responsible for vision
anterior
the motor cortex is ______ to the somatosensory cortex
somatosensory
this cortex initially processes sensory input, routing it to another more specialized cortex for further analysis
posterior
the primary sensory cortex is ________ to the primary motor cortex, separated by the central sulcus
associative
each brain region has an _______ cortex, which assesses signals from the primary respective cortex and plans a reponse
6
how many layers is the cortex?
3, 5
which layers of the cortex contain pyramidal neurons with very long axons
thalamus
this part of the brain acts as the sensory relay station
hypothalamus, pituitary gland
this part of the brain acts as the neurohormone center, regulating biological rhythms
limbic system
this part of the brain acts as the center for emotion and learning
amygdala, hippocampus, cingulate gyrus
these three regions make up the limbic system
amygdala
this part of the brain acts as the center for negative emotion, fear, anxiety
hippocampus
this part of the brain acts as the center for learning and memory
cingulate gyrus
this part of the brain acts as the center for attention
basal ganglia
this part of the brain regulated motor control
caudate
this part of the basal ganglia regulates habit formation
substantia nigra
this part of the basal ganglia makes dopamine
substantia nigra
brain region heavily impacted by Parkinson’s
midbrain
this part of the brainstem controls visual and auditory information processing
pons
this part of the brainstem controls motor control and sensory
nuclei, alongside cranial nerves
medulla
this part of the brainstem controls the most basic life functions, such as heart rate and breathing
cerebellum
this brain region controls fine motor control, gait, balance, and muscle coordination
cranial nerves
these nerves control and receive sensory info from the face
vagus nerve
this cranial nerve communicates bidirectionally with internal organs
action potential
term used to describe the electrical impulse that travels down a cell
ATP
pumps use ____ to function, channels do not
K+, proteins
at rest there are more of this cation and biomolecule in the cell
Na+, Ca+, Cl-
at rest there are more of these 2 cations and anion outside the cell
sodium potassium pump
this pump is constantly using 1 ATP to push things in and out of the cell
3 Na+, 2 K+
the sodium potassium pump moves (#) ____ out of the cell while simultaneously moving (#) _____ into the cell at the cost of 1 ATP
diffusion
this process describes the passive movement of molecules down the concentration gradient
chemical
this driving force refers to the tendency for molecules to flow from a high to low concentration
electrical
this driving force refers to the tendency for molecules to be attracted toward opposite forces and repulsed by like
-65
resting membrane potential in a neuron is around ___ mV